Researchers Database
YAZAWA TAKUYA
Affiliation： Department of Pathology Position： Professor | |||
Last Updated :2025/06/17
Research achievements
Awards
Published Papers
- Endocrine secretory granule structures form in the presence of granule-content substances under REST-knockout and PROX1-expressing conditions, Ishii J, Sato-Yazawa H, Kashiwagi K, Miyazawa T, Iwamoto M, Miyata-Hiramatsu C, Konno K, Miyata S, Kamimura T, Yazawa T, Dokkyo Medical Journal, 2025
- Claudin 18.2 inhibits the proliferation of small-cell lung cancer cells via G0/G1 cell-cycle arrest, Kashiwagi K, Miyazawa T, Sato-Yazawa H, Ishii J, Kohno K, Konno K, Miyata-Hiramatsu C, Kamimura T, Miyata M, Yazawa T, Dokkyo Medical Journal, 3(1), 16-23, Mar. 2024
- A high fraction of inspired oxygen does not mitigate atelectasis-induced lung tissue hypoxia or injury in experimental acute respiratory distress syndrome, Tojo K, Yazawa T, Sci Rep, 15(1), 1906, Jan. 2025
- Histology and chronological magnetic resonance images of congenital spiral deformity: An experimental study in mice model, Ueda H,Iimura T, Inami S, Moridaira H, Yazawa T, Seo Y, Taneichi H, BMC Musculoskeletal Disorders, 25, 334, Apr. 2024
- 56(2), 148-152, Feb. 2024
- Development of the human medullary arcuate nucleus from mid-gestation to the perinatal period: A morphometric study, Yamaguchi K, Yazawa T, Neurosci Let, 818, 137537, Jan. 2024
- Multilayered gel-spotting device for in vitro reconstruction of hair follicle-like microstructure, Sugeno A, Sumi T, Sato-Yazawa H, Yazawa T, Inoue H, Miyata S, Micromachines, 14(9), 1651, 22 Aug. 2023
- Development of the human perihypoglossal nuclei from mid-gestation to perinatal period: A morphological study, Yamaguchi K, Yazawa T, Neuroscience Letter, Jul. 2022
- REST inactivation and coexpression of ASCL1 and POU3F4 are necessary for the complete transformation of RB1/TP53-inactivated lung adenocarcinoma into neuroendocrine carcinoma, Masawa M, Sato-Yazawa H, Kashiwagi K, Ishii J, Miyata-Hiramatsu C, Iwamoto M, Kohno K, Miyazawa T, Onozaki M, Noda S, Shimizu Y, Niho S, Yazawa T, Am J Pathol, Jun. 2022
- LXRβ activation inhibits proliferation of small cell lung cancer cells through depletion of cellular cholesterol, Kashiwagi K, Sato-Yazawa H, Ishii J, Kohno K, Tatsuka I, Miyazawa T, Takagi M, Chiba H, Yazawa T, Anticancer Research, Jun. 2022
- Endocrine secretory granule production is caused by a lack of REST and intragranular secretory content and accelerated by PROX1, Ishii J, Sato-Yazawa H, Kashiwagi K, Nakadate K, Iwamoto M, Kohno K, Miyata-Hiramatsu C, Masawa M, Onozaki M, Noda S, Miyazawa T, Takagi M, Yazawa T, J Mol Histol, 53, 437-448, May 2022
- Histopathological evaluation of the effectiveness of oral Eppikajutsuto treatment for lymphatic malformation., Matsudera Shotaro;Sato-Yazawa Hanako;Terada Misao;Yamaguchi Takeshi;Tani Yukiko;Watanabe Shun;Kashiwagi Korehito;Ishii Jun;Ito Yoshifumi;Ogino Kei;Okamoto Kentaro;Nakajima Masanobu;Morita Shinji;Yamaguchi Satoru;Kuroda Hajime;Tsuchioka Takashi;Kojima Kazuyuki;Yazawa Takuya, Journal of Pediatric Surgery, Sep. 2021
- Utility of a Single Particle Isolation System in Genome-editing and Gene-transfection Experiments, Hanako Sato-Yazawa, Korehito Kashiwagi, Jun Ishii, Meitetsu Masawa, Masato Onozaki, Chie Miyata-Hiramatsu, Tadasuke Miyazawa, Mai Sakaguchi, Takuya Yazawa, Dokkyo Journal of Medical Sciences, Jul. 2021
- 54, 128-139, Jul. 2020
- 2, 270, Jul. 2019
- 61(7), 264-271, Jul. 2017
- 64(6), 179-185, Jun. 2017
- 67(5), 278-279, May 2017
- 55(6), 878-888, Dec. 2016
- CD8-positive T-cell lymphoproliferative disorder associated with Epstein-Barr virus-infected B-cells in a rheumatoid arthritis patient under methotrexate treatment, Koji H, Yazawa T, Nakabayashi K, Fujioka Y, Kamma H, Yamada A, Mod Rheumatol, 26(2), 271-275, Mar. 2016
- PROX1 promotes secretory granule formation in medullary thyroid cancer cells, Ishii J, Yazawa T, Chiba T, Shishido-Hara Y, Arimasu Y, Sato H, Kamma H, Endocrinology, 157(3), 1289-1298, Mar. 2016
- Adrenaline aggravates lung injury caused by liver ischemia-reperfusion and high-tidal-volume ventilation in rats, Ota S, Yazawa T, Tojo K, Baba Y, Uchiyama M, Goto T, Kurahashi K, J Intensive Care, 4, 8, Jan. 2016
- Atelectasis causes alveolar hypoxia-induced inflammation during uneven mechanical ventilation in rats, Tojo K, Nagamine Y, Yazawa T, Mihara T, Baba Y, Ota S, Goto T, Kurahashi K, Intensive Care Med Exp, 3(1), 56, Dec. 2015
- High-grade fetal adenocarcinoma of the lung is a tumour with a fetal phenotype that shows diverse differentiation, including high-grade neuroendocrine carcinoma: a clinicopathological, immunohistochemical and mutational study of 20 cases, Suzuki M, Yazawa T, Ota S, Morimoto J, Yoshino I, Yamanaka S, Inayama Y, Kawabata Y, Shimizu Y, Komatsu M, Notohara K, Koda K, Nakatani Y, Histopathology, 67(6), 806-816, Jun. 2015
- An inflammatory pseudotumor arising from pterygopalatine fossa with invasion to the maxillary sinus and orbital cavity, Yokoi H, Yazawa T, Matsumoto Y, Ikeda T, Fujiwara M, Ohkura Y, Kohno N, Case Rep Otolaryngol, 2015, 950823, Jun. 2015
- Recent advances in histogenesis research of lung neuroendocrine cancers: evidence obtained from functional analyses of primitive neural/neuroendocrine cell-specific transcription factors, Yazawa T, Pathol Int, 65(6), 277-285, Jun. 2015
- Edaravone prevents lung injury induced by hepatic ischemia-reperfusion, Uchiyama M, Tojo K, Yazawa T, Ota S, Goto T, Kurahashi K, J Surg Res, 194(2), 551-557, Apr. 2015
- Class III/IV POU transcription factors expressed in small cell lung cancer cells are involved in proneural/neuroendocrine differentiation, Ishii J, Sato H, Yazawa T, Shishido-Hara Y, Hiramatsu C, Nakatani Y, Kamma H, Pathol Int, 64(9), 415-422, Sep. 2014
- Expression of developing neural transcription factors in lung carcinoid tumors, Endo T, Yazawa T, Shishido-Hara Y, Fujiwara M, Shimoyamada H, Ishii J, Sato H, Tachibana K, Takei H, Kondo H, Goya T, Endo S, Kamma H, Pathol Int, 64(8), 365-374, Aug. 2014
- JC virus inclusions in progressive multifocal leukoencephalopathy: scaffolding promyelocytic leukemia nuclear bodies grow with cell cycle transition through an S-to-G2-like state in enlarging oligodendrocyte nuclei, Shishido-Hara Y, Yazawa T, Nagane M, Higuchi K, Abe-Suzuki S, Kurata M, Kitagawa M, Kamma H, Uchihara T, J Neuropathol Exp Neurol, 73(5), 442-453, May 2014
- Prenatal diagnosis of umbilical artery thrombosis, Tanaka K, Tanigaki S, Matsushima M, Miyazaki N, Hashimoto R, Izawa T, Sakai K, Yazawa T, Iwashita M, Fetal Diagn Ther, 35(2), 148-150, Feb. 2014
- 83, 32-38, 2014
- 63, 158-168, 2013
- 93, 408-421, 2013
- 62, 232-245, 2012
- 61, 19-27, 2011
- 2, 719-724, 2011
- 45, 489-497, 2011
- 298, C450-C456, 2010
- 177, 70-83, 2010
- 3, 348-366, 2010
- 4, 32-42, 2010
- 28, 672-679, 2010
- 34, 243-255, 2010
- 59, 28-37, 2009
- 107, 81-91, 2009
- 175, 976-987, 2009
- 175, 867-881, 2009
- 66, 287-291, 2009
- 175, 2646-2656, 2009
- 65, 355-362, 2009
- 24, 216-222, 2009
- 171, 1705-1712, 2007
- 18, 130-141, 2007
- 87, 189-198, 2007
- 292, L625-L631, 2007
- 169, 1550-1566, 2006
- 37, 25-35, 2005
- 64, 7910-7917, 2004
- 287, 402-410, 2004
- 45, 325-337, 2004
- 164, 91-100, 2004
- 39, 159-164, 2003
- 163, 373-376, 2003
- 31, 204-212, 2002
- 161, 291-300, 2002
- 93, 184-189, 2002
- 17, 1121-1127, 2002
- 16, 335-343, 2001
- 34, 233-241, 2001
- 33, 233-241, 2001
- 34, 59-65, 2001
- 127, 3913-3921, 2000
- 192, 26-31, 2000
- 187, 191-199, 1999
- 246, 399-411, 1999
- 37, 85-90, 1998
- 18, 1027-1030, 1998
- 18, 1043-1046, 1998
- 10, 1566-1571, 1997
- 4, 199-202, 1995
- 43, 28-35, 1993
- 1, 289-296, 1993
- 60, 407-412, 1991
- 32, 694-695, 2014
- 29, 57-61, 2012
- 24, 784-788, 2010
- 55, 204-210, 2010
- 27, 460-467, 2009
- 53, 194-202, 2008
- 34, 17-21, 2006
- 51, 78-84, 2006
- 50, 89-97, 2005
- 53, 288-294, 2004
- 44, 213-217, 2004
- 52, 806-811, 2003
- 51, 1288-1293, 2002
- 44, 629-636, 1998
- 21 Supplement II, 140-147, 1994
- 28, 892-903, 1993
- 32, 193-199, 1992
- 38特集III, 140-145, 1991
Original paper
- What is the cell of origin of lung neuroendocrine carcinoma?, Yazawa T, 63(1), 40-41, Jan. 2025
- Reprogramming phenomena found in lung cancers, 55(9), 789-793, 20 Sep. 2023
Review paper
- Resolution of pelvic postoperative spindle cell nodule with sarcomatous onset after 9 years of follow-up, Matsuoka A, Mitsuhashi A, Usui H, Otsuka S, Nishikimi K, Tate S, Okuya R, Yazawa T, Shozu M, Koga K, J Obstet Gynecol Res, 51(2), e16238, Feb. 2025
- Spontaneous transformation from lung adenocarcinoma to MYC-amplified large cell neuroendocrine carcinoma, Yamakado T, Sato-Yazawa H, Ishii J, Kashiwagi K, Kimura T, Tanei Z, Yazawa T, Ishida Y, Tanaka S, Pathol Int, 75(2), 105-113, Jan. 2025
- Unencapsulated thymoma: a case report, Yamamot S, Mizutani E, Morita R, Kodama M, Abe K, Yazawa T, Journal of Surgical Case Reports, 10, 1-3, Oct. 2023
- Pulmonary langerhans cell histiocytosis as differential diagnosis for multiple colorectal metastases of lung: A case report, 36(7), 754-759, 25 Jul. 2022
Case report
- 65, 277-285, Jun. 2015
- 125, e503-e506, 2012
- 206, 121-129, 2010
- 42(Suppl 2), E65-E66, 2010
- 3, 214-217, 2010
- 20, 101-107, 2009
- 66, 275-281, 2009
- 2, 106-114, 2008
- 36, 702-705, 2005
- 53, 58-65, 2003
- 14, 133-139, 2003
- 16, 335-343, 2001
- 20, 527-530, 2000
- 92, 882-884, 1998
- 57, 1054-1055, 1994
- 105, 307-308, 1994
- 10, 320-324, 1994
- 10, 101-106, 1993
- 419, 513-518, 1991
- 55, 233-240, 2015
- 60, 513-516, 2009
- 26, 69-73, 2006
- 42, 266-271, 2004
- 78, 525-529, 1998
- 34, 1390-1394, 1996
- 40, 949-952, 1995
- 92, 997-1001, 1995
- 5, 661-665, 1995
- 56, 233-237, 1995
- 85, 508-511, 1994
- 53, 145-148, 1994
- 27, 75-78, 1994
- 16, 646-651, 1994
- 6, 403-406, 1993
- 38, 625-628, 1993
- 39, 67-73, 1993
- 38, 737-740, 1993
- 15, 16-17, 1993
- 31, 957-961, 1991
- 30, 754-759, 1991
Other
- Enhancement of glycolysis by inhibition of oxygen-sensing prolyl hydroxylases protects alveolar epithelial cells from acute lung injury., Tojo Kentaro;Tamada Nao;Nagamine Yusuke;Yazawa Takuya;Ota Shuhei;Goto Takahisa, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(4), 2258-2268, Apr. 2018
- Clinicopathological, immunohistochemical, and mutational analyses of pulmonary enteric adenocarcinoma: usefulness of SATB2 and β-catenin immunostaining for differentiation from metastatic colorectal carcinoma., Matsushima Jun;Yazawa Takuya;Suzuki Masaki;Takahashi Yoko;Ota Satoshi;Nakajima Takahiro;Yoshino Ichiro;Yokose Tomoyuki;Inoue Toru;Kawahara Kunimitsu;Nakatani Yukio, Human pathology, 64, 179-185, 2017
Unclear
Books etc
- Joint work, Jun. 2008, 614-618
- Joint work, Jun. 2008, 110-111
- Joint work, Jun. 2008
- Joint work, Jun. 2008, 100-105
- Joint work, Jun. 1995, 117-121
Industrial Property Rights
Social contributions
Social Contribution
Academic Contribution
- Academic society etc, 17 Oct. 2025, 18 Oct. 2025, Not contributing to international academic
- Reviewer of iScience, Peer review etc, 19 May 2022, 27 Oct. 2022, International academic contribution
- Reviewer of Molecular Immunology, Peer review etc, 02 May 2022, 07 May 2022, International academic contribution
- Reviewer of Dokkyo Medical Journal, Peer review etc, 28 Mar. 2022, 25 May 2022, International academic contribution
- Reviewer of Dokkyo Medical Journal, Peer review etc, 28 Mar. 2022, 20 May 2022, International academic contribution
- Reviewer of Clinical Case Report, Peer review etc, 06 Mar. 2022, 13 Mar. 2022, International academic contribution
- Reviewer of Respiratory Investigation, Peer review etc, 03 Oct. 2021, 13 Oct. 2021, International academic contribution
- Reviewer of Acta Histochemica, Peer review etc, 15 Oct. 2020, 20 Oct. 2020, International academic contribution
- Reviewer of Cancer Science, Peer review etc, 15 Sep. 2020, 23 Sep. 2020, International academic contribution
- Reviewer of Cancer Science, Peer review etc, 05 Feb. 2020, 18 Feb. 2020, International academic contribution