Researchers Database
ISHIKAWA TOMOHIRO
Affiliation： Department of Microbiology Position： Senior Assistant Professor | |||
Last Updated :2024/06/11
Research achievements
Published Papers
- Characterization of genotype V Japanese encephalitis virus isolates from Republic of Korea., Lee AR, Kim SH, Hong SY, Lee SH, Oh JS, Lee KY, Kim SJ, Ishikawa T, Shim SM, Lee HI, Seo SU., Emerg Microbes Infect., 13(1), 2362392, Dec. 2024
- Dissemination of the Flavivirus Subgenomic Replicon Genome and Viral Proteins by Extracellular Vesicles., Ishikawa T, Narita K, Matsuyama K, Masuda M., Viruses, 16(4), 524, 28 Mar. 2024
- Flavivirus recruits the valosin-containing protein-NPL4 complex to induce stress granule disassembly for efficient viral genome replication., Arakawa Masashi;Tabata Keisuke;Ishida Kotaro;Kobayashi Makiko;Arai Arisa;Ishikawa Tomohiro;Suzuki Ryosuke;Takeuchi Hiroaki;Tripathi Lokesh P;Mizuguchi Kenji;Morita Eiji, The Journal of biological chemistry, 298(3), 101597, 2022
- Characterization of Prototheca CYP51/ERG11 as a possible target for therapeutic drugs, Takahisa Watanabe, Tomohiro Ishikawa, Hirotaka Sato, Noriyuki Hirose, Lisa Nonaka, Kaori Matsumura, Akira Masubuchi, Kazuko Nishimura, Michiaki Masuda, Med Mycol, 59(9), 855-863, 2021
- Effects of the Japanese Encephalitis Virus Genotype V-Derived Sub-Viral Particles on the Immunogenicity of the Vaccine Characterized by a Novel Virus-Like Particle-Based Assay, Honjo S, Masuda M, Ishikawa T, Vaccines (Basel), 7(3), E81, Aug. 2019
- 11, 312, Jul. 2019
- Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251, Ueda Y, Gu W, Dansako H, Kim HS, Yoshizaki S, Okumura N, Ishikawa T, Nishitsuji H, Kato F, Hishiki T, Satoh S, Ishii K, Masuda M, Shimotohno K, Ikeda M, Kato N, Biochem Biophys Rep, 15, 1-6, Sep. 2018
- Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum, Tabata K, Arimoto M, Arakawa M, Nara A, Saito K, Omori H, Arai A, Ishikawa T, Konishi E, Suzuki R, Matsuura Y, Morita E, Cell Rep, 16(9), 2339-2347, Aug. 2016
- Prototheca miyajii sp. nov., isolated from a patient with systemic protothecosis, Masuda M, Hirose N, Ishikawa T, Ikawa Y, Nishimura K, Int J Syst Evol Microbiol, 66(3), 1510-1520, Mar. 2016
- Construction of an infectious molecular clone of Japanese encephalitis virus genotype V and its derivative subgenomic replicon capable of expressing a foreign gene, Ishikawa T, Abe M, Masuda M, Virus Res, 195, 153-161, Jan. 2015
- Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon, Suzuki R, Ishikawa T, Konishi E, Matsuda M, Watashi K, Aizaki H, Takasaki T, Wakita T, J Gen Virol, 95(Pt 1), 60-65, Jan. 2014
- Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling, Winkelmann ER, Widman DG, Xia J, Ishikawa T, Miller-Kittrell M, Nelson MH, Bourne N, Scholle F, Mason PW, Milligan GN, Vaccine, 30(8), 1465-1475, Feb. 2012
- Enhancing the utility of a prM/E-expressing chimeric vaccine for Japanese encephalitis by addition of the JEV NS1 gene, Ishikawa T, Wang G, Widman DG, Infante E, Winkelmann ER, Bourne N, Mason PW, Vaccine, 29(43), 7444-7455, Oct. 2011
- Needle-free jet injection of small doses of Japanese encephalitis DNA and inactivated vaccine mixture induces neutralizing antibodies in miniature pigs and protects against fetal death and mummification in pregnant sows, Imoto J, Ishikawa T, Yamanaka A, Konishi M, Murakami K, Shibahara T, Kubo M, Lim CK, Hamano M, Takasaki T, Kurane I, Udagawa H, Mukuta Y, Konishi E, Vaccine, 28(46), 7373-80, Oct. 2010
- Evaluation of RepliVAX WN, a single-cycle flavivirus vaccine, in a non-human primate model of West Nile virus infection, Widman DG, Ishikawa T, Giavedoni LD, Hodara VL, Garza Mde L, Montalbo JA, Travassos Da Rosa AP, Tesh RB, Patterson JL, Carrion R Jr, Bourne N, Mason PW, Am J Trop Med Hyg, 82(6), 1160-1167, Jun. 2010
- Conjugation to nickel-chelating nanolipoprotein particles increases the potency and efficacy of subunit vaccines to prevent West Nile encephalitis, Fischer NO, Infante E, Ishikawa T, Blanchette CD, Bourne N, Hoeprich PD, Mason PW, Bioconjug Chem, 21(6), 1018-1022, Jun. 2010
- RepliVAX WN, a single-cycle flavivirus vaccine to prevent West Nile disease, elicits durable protective immunity in hamsters, Widman DG, Ishikawa T, Winkelmann ER, Infante E, Bourne N, Mason PW, Vaccine, 27(41), 5550-5553, Sep. 2009
- Construction and evaluation of a chimeric pseudoinfectious virus vaccine to prevent Japanese encephalitis, Ishikawa T, Widman DG, Bourne N, Konishi E, Mason PW, Vaccine, 26(22), 2772-2781, May 2008
- Construction and characterization of a second-generation pseudoinfectious West Nile virus vaccine propagated using a new cultivation system, Widman DG, Ishikawa T, Fayzulin R, Bourne N, Mason PW, Vaccine, 26(22), 2762-2771, May 2008
- Co-immunization with West Nile DNA and inactivated vaccines provides synergistic increases in their immunogenicities in mice, Ishikawa T, Takasaki T, Kurane , INukuzuma S, Kondo T, Konishi E, Microbes Infect, 9(9), 1089-1095, Jul. 2007
- Mosquito cells infected with Japanese encephalitis virus release slowly-sedimenting hemagglutinin particles in association with intracellular formation of smooth membrane structures, Ishikawa T, Konishi E, Microbiol Immunol, 50(3), 211-223, 2006
Original paper
- Potential chemotherapeutic targets for Japanese encephalitis: current status of antiviral drug development and future challenges, Ishikawa T, Konishi E, Expert Opin Ther Targets, 19(10), 1379-1395, Oct. 2015
- Japanese encephalitis: epidemiology, prevention and current status of antiviral drug development., Ishikawa T, Konishi E, Expert Opin Orphan Drugs, 2(9), 923-936, Sep. 2014
- A review of successful flavivirus vaccines and the problems with those flaviviruses for which vaccines are not yet available, Ishikawa T, Yamanaka A, Konishi E, Vaccine, 32(12), 1326-1337, Mar. 2014
- Combating Japanese encephalitis: Vero-cell derived inactivated vaccines and the situation in Japan., Ishikawa T, Konishi E, Future Virol, 5(6), 785-799, Nov. 2010
Review paper
- 48(3), 303-313, Oct. 2021
- 79(4), 547-552, Apr. 2016
- 79(4), 547-52, Mar. 2016
- 30(2), 248-254, Jan. 2014
- 29(増刊), 1055-1061, Apr. 2013
- Flaviviruses, Ishikawa T, Konishi E, Uirusu, 61(2), 221-38, Dec. 2011
Other
Books etc
Public grant (competitive fund)
- Function of Japanese encephalitis genome circularization on viral replication, 科学研究費助成事業(獨協医科大学), Tomohiro Ishikawa, 01 Apr. 2015 - 31 Mar. 2017