HIKIMA TAKUYA

Profiles

Profiles

• 氏名

  HIKIMA TAKUYA

Affiliation

• Assistant Professor

Profile and Settings

Alternate Names

• Hikima T

Affiliation

• Dokkyo Medical University, Divition for Memory and Cognitive Function, Assistant Professor

Degree

• Ph.D., Life science

Research Interests

• Dopamine
• Neurona network
• Synapse
• Imaging
• Electrophysiology
• Multisensory integration

Research Areas

• Life Science, Clinical pharmacy
• Life Science, Physiology
• Life Science, Plant molecular biology and physiology
• Life Science, Molecular biology
• Life Science, Basic brain sciences
• Life Science, Neuroscience-general, Neurophysiology

Research Experience

• Apr. 2022, 9999, Dokkyo Medical University, DIvision for Memory and Cognitive function, Associate Professor, Japan
• Nov. 2018, Feb. 2022, New York University School of Medicine, Neurosurgery, Instructor
• Jan. 2015, Oct. 2018, New York University School of Medicine, Neurosurgery, Research Associate Scientist
• Apr. 2009, Dec. 2014, Okinawa institute of science and technology graduate university, Ppostdoctoral fellow

Education

• Apr. 2004, Mar. 2009, Tohoku University of Graduate school, Life Science, 脳機能解析分野
• Apr. 2000, Mar. 2004, Tokyo University of Science, Faculty of Industrial Science and Technology, Biological Science and Technology

Association Memberships

• THE JAPAN NEUROSCIENCE SOCIETY
• PHYSIOLOGICAL SOCIETY OF JAPAN

Research achievements

Awards

• May 2016, 16th Conference of the International Society for Monitoring Molecules in Neuroscience, Best presentation Award, Detection of somatodendritic dopamine release using whole-cell recording, Takuya HIKIMA
• May 2010, the Physiological Society of Japan, Japanese Physiological Sciences Award (JPS Award),, Takuya Hikima
• Jul. 2008, IBRO, ANS/IBRO Travel Award, Takuya Hikima
• Apr. 2004, Japan Student Service Organization (JASSO), Japan Scholarship Foundation Scholarship for Graduate Students, Takuya HIKIMA

Published Papers

Original paper
• Leptin activates dopamine and GABA neurons in the substantia nigra via a local pars compacta-pars reticulata circuit, Maria Mancini; Takuya Hikima; Paul Witkovsky; Jyoti C. Patel; Dominic W. Stone; Alison H. Affinati; Margaret E. Rice, The Journal of Neuroscience, e1539242025-e1539242025, 24 Mar. 2025

  DOI
• A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortices in mice, Susumu Setogawa; Ryota Kanda; Shuto Tada; Takuya Hikima; Yoshito Saitoh; Mikiko Ishikawa; Satoshi Nakada; Fumiko Seki; Keigo Hikishima; Hideyuki Matsumoto; Kenji Mizuseki; Osamu Fukayama; Makoto Osanai; Hiroto Sekiguchi; Noriaki Ohkawa, Molecular Brain, 16(1), 03 May 2023

  DOI
• Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release, Takuya Hikima; Paul Witkovsky; Latika Khatri; Moses V Chao; Margaret E Rice, Journal of Neuroscience, 42(19), 3919-3930, May 2022

  DOI

Unclear
• Activity-dependent somatodendritic dopamine release in the substantia nigra autoinhibits the releasing neuron, Takuya Hikima; Christian R Lee; Paul Witkovsky; Julia Chesler; Konstantin Ichtchenko; Margaret E Rice, Cell Reports, 6(35), 108951, Apr. 2021

  DOI
• Lithium increases synaptic GluA2 in hippocampal neurons by elevating the delta-catenin protein, Mobeen Farooq; Seonil Kim; Sunny Patel; Latika Khatri; Takuya Hikima; Margaret E. Rice; Edward B. Ziff, NEUROPHARMACOLOGY, 113, 426-433, Feb. 2017

  DOI
• Presynaptic D1 heteroreceptors and mGlu autoreceptors act at individual cortical release sites to modify glutamate release, Takuya Hikima; Marianela Garcia-Munoz; Gordon William Arbuthnott, BRAIN RESEARCH, 1639, 74-87, May 2016

  DOI
• beta-Phorbol ester-induced enhancement of exocytosis in large mossy fiber boutons of mouse hippocampus, Takuya Hikima; Rikita Araki; Toru Ishizuka; Hiromu Yawo, JOURNAL OF PHYSIOLOGICAL SCIENCES, 59(4), 263-274, Jul. 2009

  DOI
• Molecular Determinants Differentiating Photocurrent Properties of Two Channelrhodopsins from Chlamydomonas, Hongxia Wang; Yuka Sugiyama; Takuya Hikima; Eriko Sugano; Hiroshi Tomita; Tetsuo Takahashi; Toru Ishizuka; Hiromu Yawo, JOURNAL OF BIOLOGICAL CHEMISTRY, 284(9), 5685-5696, Feb. 2009

  DOI
• Photocurrent attenuation by a single polar-to-nonpolar point mutation of channelrhodopsin-2, Yuka Sugiyama; Hongxia Wang; Takuya Hikima; Minami Sato; Jun Kuroda; Tetsuo Takahashi; Toru Ishizuka; Hiromu Yawo, PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 8(3), 328-336, 2009

  DOI
• Synaptic vesicle dynamics in the mossy fiber-CA3 presynaptic terminals of mouse hippocampus, Shigetomo Suyama; Takuya Hikima; Hiroyuki Sakagami; Toru Ishizuka; Hiromu Yawo, NEUROSCIENCE RESEARCH, 59(4), 481-490, Dec. 2007

  DOI
• Transgenic mouse lines expressing synaptopHluorin in hipplpcarnpus and cerebellar cortex, R Araki; H Sakagami; Y Yanagawa; T Hikima; T Ishizuka; H Yawo, GENESIS, 42(2), 53-60, Jun. 2005

  DOI

MISC

• Synaptic vesicle dynamics and its plasticity, Takuya Hikima; Rikita Araki; Toru Ishizuka; Hiromu Yawo, JOURNAL OF PHYSIOLOGICAL SCIENCES, 60, S47-S47, 2010
• Glu-97 of channelrhodopsin-2 is one of the molecular determinants involved in the ion flux, Toru Ishizuka; Yuka Sugiyama; Hongxia Wang; Takuya Hikima; Minami Sato; Jun Kuroda; Tetsuo Takahashi; Hiromu Yawo, NEUROSCIENCE RESEARCH, 65, S196-S196, 2009

  DOI
• Molecular determinant differenciating Chlamydomonas channelrhodopsins, Hongxia Wang; Yuka Sugiyama; Takuya Hikima; Eriko Sugano; Hiroshi Tomita; Tetsuo Takahashi; Toru Ishizuka; Hiromu Yawo, NEUROSCIENCE RESEARCH, 65, S196-S196, 2009

  DOI
• PHOTOCURRENT ATTENUATION BY THE G1u97Ala MUTAION OF CHANNELRHODOPSIN-2, Yuka Sugiyama; Hongxia Wang; Takuya Hikima; Minami Sato; Jun Kuroda; Tetsuo Takahashi; Toru Ishizuka; Hiromu Yawo, JOURNAL OF PHYSIOLOGICAL SCIENCES, 59, 396-396, 2009
• PKC-dependent reorganization of vesicular dynamics during presynaptic unsilencing, Takuya Hikima; Rikita Araki; Toru Ishizuka; Hiromu Yawo, NEUROSCIENCE RESEARCH, 61, S79-S79, 2008
• Activation of presynaptically silent synapses - One of underlying mechanisms enhancing mossy fiber transmission in the hippocampus, Takuya Hikima; Rikita Araki; Toru Ishizuka; Hiromu Yawo, NEUROSCIENCE RESEARCH, 58, S190-S190, 2007
• Vesicular dynamics and its plasticity in the hippocampal synapse, Hiromu Yawo; Shigetomo Suyama; Takuya Hikima; Yuka Sugiyama; Hiroyuki Sakagami; Toru Ishizuka, NEUROSCIENCE RESEARCH, 58, S14-S14, 2007
• S2f1-3 Imaging of synaptic network plasticity in the CNS by probing vesicle dynamics, Yawo Hiromu; Araki Rikita; Hikima Takuya; Ishizuka Toru, 生物物理, 46(2), S125, 2006

Books etc

• Imaging of neuronal activity in freely behaving animals using miniature microscope, Joint work, Takuya Hikima; NOriaki Ohkawa, 「臨床精神医学」第52巻3号（2023年3月号） p327-330・株式会社アークメディア, Mar. 2023

Presentations

• Multisensory information processing and integration in primary sensory cortices of mice., 引間 卓弥; 竹本 雄貴; 濱高 靖浩; 斎藤 喜人; 南島 遼; 深山 理; 関口 寛人; 大川 宜昭, APPW2025, 19 Mar. 2025, 17 Mar. 2025, 19 Mar. 2025, Poster presentation

  添付ファイルのURL
• Laterality of multimodal sensory representation in Alzheimer’s disease model mice., 竹本 雄貴; 引間 卓弥; 川淵 公美子; 瀬戸川 将; 濱髙 靖浩; 斎藤 喜人; 石河 三貴子; 上吉原 千賀子; 齊藤 貴志; 笹栗 弘貴; 西道 隆臣; 関口 寛人; 小山内 実; 大川 宜昭, APPW2025, 17 Mar. 2025, 20 Mar. 2025, Poster presentation
• 多点LEDプローブ・多点皮質脳波電極シートを活用した神経活動の局所的介入と多点計測系の構築, 山田 晃大; 引間 卓弥; 奥井 歩夢; 濱高 靖浩; 西川 敦; Loesing A.; 大川 宜昭; 関口 寛人, 第72回応用物理学会春季学術講演, Mar. 2025, 14 Mar. 2025, 17 Mar. 2025, Oral presentation
• 未知な神経・脳機能を解き明かし、病態生理の理解に迫る, 引間卓弥, 日本病態生理学会 冬の学校2024, 26 Dec. 2024, 26 Dec. 2024, 27 Dec. 2024, Invited oral presentation
• アルツハイマー病モデルマウスにおける海馬と一次感覚野での感覚刺激に応じた特徴的神経活動, 竹本 雄貴; 引間 卓弥; 大川 宜昭, 第52回 獨協医学会学術集会, 07 Nov. 2024, Oral presentation
• 多感覚応答の同時記録を可能にする多点皮質脳波電極シートの開発, 濱高 靖浩; 引間 卓弥; 神田 稜太; 大川 宜昭; 関口 寛人, 第85回応用物理学会秋季学術講演, Sep. 2024, 16 Sep. 2024, 20 Sep. 2024, Oral presentation
• Chronic recording for multisensory neural activity in mice using developed micro-ECoG device, 引間 卓弥; 竹本 雄貴; 斎藤 喜人; 濱高 靖浩; 関口 寛人; 大川 宜昭, NEURO2024, 25 Jul. 2024, 24 Jul. 2024, 27 Jul. 2024, Poster presentation

  添付ファイルのURL
• Flexible MicroLED array film adhering to the brain surface for in vivo optogenetic stimulation, Kanda R; Kitade T; Nishikawa A; Loesing A; Sirai M; Kobayashi H; Fukunaga I; Hikima T; Ohkawa N; Sekiguchi H, The 14th International Conference on Nitride Semiconductors (ICNS-14), Nov. 2023, 12 Nov. 2023, 17 Nov. 2023
• マウスの多感覚応答記録を可能にする皮質脳波記録シートの開発, 濱高 靖浩; 神田 稜太; 引間 卓弥; 大川 宜昭; 関口 寛人, 第42回電子材料シンポジウム, Oct. 2023, Oct. 2023, Poster presentation
• マイクロLEDプローブを用いた特定部位への選択的光刺激の検証, 竹内 響; 大屋 翔; 西川 敦; Loesing Alexander; 引間 卓弥; 大川 宜昭; 関口 寛人, 第84回応用物理学会秋季学術講演会, Sep. 2023, Sep. 2023
• Development of flexible micro-ECoG device for multisensory neural activity from parietal to temporal cortex in mice, Takuya Hikima; Susumu Setogawa; Ryota Kanda; Shuto Tada; Yoshito Saitoh; Mikiko Ishikawa; Satoshi Nakada; Fumiko Seki; Keigo Hikishima; Hideyuki Matsumoto; Kenji Mizuseki; Osamu Fukayama; Makoto Osanai; Hiroto Sekiguchi; Noriaki Ohkawa, The 46th Annual Meeting of the Japan Neuroscience Society, 03 Aug. 2023, 01 Aug. 2023, 04 Aug. 2023, Poster presentation

  添付ファイルのURL
• The primary source and molecular requirements of somatodendritic dopamine release, Takuya Hikima; Paul Witkovsky; Margaret. E. Rice, The 100th Anniversary Annual Meeting of The Physiological Society of Japan, 14 Mar. 2023, 14 Mar. 2023, 16 Mar. 2023, Poster presentation

  添付ファイルのURL
• Syt7 is the primary Ca2+ sensor for phasic somatodendriticDA release, Takuya Hikima; Witkovsky Paul; Rice Margaret, NEURO2022, 01 Jul. 2022, 30 Jun. 2022, 03 Jul. 2022, Poster presentation

  添付ファイルのURL
• Regulation of somatodendritic dopamine release from the inside, Rice M.E; Witkovsky P.W; Hikima T, Monitoring Molecules in Neuroscience: 18th International Conference, 2022, 2022, Invited oral presentation
• Somatodendritic DA release, Takuya HIKIMA, The Tokyo University, Graduate School of Medicine and Faculty of Medicine, Department of Cellular neurobiology, 23 Jan. 2020, Public discourse
• Somatodendritic DA release, Takuya HIKIMA, The Jikei University school of Medicine, 21 Jan. 2020, Public discourse
• somatodendritic dopamine release, Takuya HIKIMA, NYU Neuroscience Meeting, New York, USA, Dec. 2019, Oral presentation, True
• Evaluation of synaptotagmin7 in the unique properties of somatodendritic dopamine release, Takuya HIKIMA; ‚; Witkovsky P; Ichtchenko K; Rice ME, Center for Cognitive Neurology (Annual Research Day), Sep. 2019, True
• Evaluation of synaptotagmin7 function in the unique properties of somatodendritic dopamine release, Takuya HIKIMA; Witkovsky P; Ichtchenko K; Rice ME, The 42th Annual Meeting of the Japan Neuroscience Society, Jul. 2019, Poster presentation, False
• Evaluation of synaptotagmin7 function in the unique properties of somatodendritic dopamine release, Hikima T‚; Witkovsky P; Ichtchenko K; Rice ME, 12th Annual retreat NYU Neuroscience, New York, USA, 04 Apr. 2019, Poster presentation, False
• Modulation of a local SNc SNr circuit by leptin, M. Mancini; Takuya HIKIMA; D. Stone; P. Witkovsky; M. Rice, IBAGS 2019, Apr. 2019, Poster presentation, Biarritz, France, Cross-talk between metabolic hormones and midbrain dopamine (DA) neurons is increasingly well-appreciated. The adipose-tissue derived hormone leptin has been demonstrated to play a role in regulating DA synthesis and somatodendritic DA stores in ventral tegmental area (VTA), but whether leptin influences the activity of DA neurons in substantia nigra pars compacta (SNc) or other aspects of basal ganglia circuitry is unknown. Using whole-cell patch clamp recordings in ex vivo midbrain slices, we found that leptin increased DA neuron excitability and somatodendritic DA release in the SNc. This enhancement was lost after intracellular application of a leptin receptor (OBR) antibody or antagonism of IP3 receptors. These data implicate OBR-dependent activation of intracellular calcium (Ca2+) stores in both effects of leptin. Leptin also caused an increase in substantia nigra pars reticulata (SNr) GABA neuron excitability. Strikingly, however, this proved to be an indirect effect that was prevented in the presence of a D1 receptor antagonist, by DA depletion, or by application of a TRPC3 channel blocker. Thus, leptin enhances somatodendritic SNc Da neuron activity and DA release, which leads to excitation of SNr GABA neurons via D1 receptors and downstream TRPC3 channel activation, via a previously described local circuit (Zhou et al. 2009). These data suggest that leptin could act through this novel SNc-SNr circuit, to regulate motor activity. Moreover, an imbalance in energy status during disease states, including obesity and Parkinson’s disease, that include altered leptin levels or signaling would influence DA neuron activity, and impact motor function in these disorders., True
• Evaluation of synaptotagmin 7 in the unique properties of somatodendritic dopamine release, T. Hikima; P Witkovsky; K. Ichtchenko; M. Rice, IBAGS 2019, Apr. 2019, Poster presentation, Biarritz, France, Midbrain dopamine (DA) neurons in the substantia nigra pars compacta (SNc) exhibit somatodendritic release of DA. Released DA acts at D2 autoreceptors to regulate neuronal firing patterns that regulate DA release throughout the brain. We reported previously that: 1) the Ca2+ dependence of somatodendritic DA release differs from that of axonal release; 2) aspects of molecular organization for somatodendritic DA release are distinct from those for conventional synaptic release. Additional evidence from our group implies that D2 receptors on a given DA neuron are activated primary by DA released from that same cell, literally autoregulation, via exocytosis. Here we focused on synaptotagmin 7 (Syt7), a high affinity Ca2+ sensor required for neurotransmitter release, to test the hypothesis that Syt7 contributes to the unique Ca2+ dependence of somatodendritic DA release in the SNc. Immunohistochemical studies confirmed the presence of Syt7 in somata and dendrites of SNc DA neurons. We then evaluated Syt7 function using voltage-clamp recording of SNc DA neurons in acute midbrain slices. Locally evoked D2 DA-dependent inhibitory currents (D2ICs) mediated by D2 receptor G-protein coupled K+ (GIRK) channels as monitored an index of somatodendritic DA release. Evoked D2IC amplitude was attenuated when an antibody against Syt7 (anti-Syt7) was included in the recording pipette. This attenuation was prevented when the blocking peptide was included with anti-Syt7 in the pipette. Consistent with our previous finding in control recordings, D2ICs persisted in low extracellular Ca2+ concentrations ([Ca2+ ]o) that do not support axonal DA release. However, this Ca2+ dependence was lost when anti-Syt7 was applied via the recording pipette. Persistent DA release in low [Ca2+]o sensitivity of evoked DA release was also lost in heterozygous Syt7 mutant mice. Thus, these data support a key role for Syt7 in SNc DA neurons in the unique Ca2+ dependence of somatodendritic DA release., True
• Physiological role of somatodendritic dopamine release: true auto regulation of neural activity, Takuya H; Ichtchenko K; Rice ME, The 41th Annual Meeting of the Japan Neuroscience Society, Kobe Japan, Aug. 2018, Poster presentation, False

  添付ファイルのURL
• Physiological role of somatodendritic dopamine release: true auto regulation of neural activity, Hikima T; Witkovsky P; Ichtchenko K; Rice ME, Gordon Research Seminar on Basal Ganglia, Ventura, USA, Mar. 2018, Poster presentation, True
• Physiological role of somatodendritic dopamine release: true autoregulation of neural activity, Hikima T‚ Lee CR; Ichtchenko K; Rice ME, The 94th Annual Meeting of the Physiological Society of Japan, 30 Mar. 2017, Poster presentation, False
• Detection of somatodendritic dopamine release using whole-cell recording, Hikima T‚ Lee CR; Vazquez-Cintron, EJ; Ichtchenko K; Rice ME, 16th Conference of the International Society for Monitoring Molecules in Neuroscience, Gothenburg, Sweden, May 2016, Poster presentation, True
• DETECTION OF SOMATODENDRITIC DOPAMINE RELEASE USING WHOLE-CELL RECORDING: A ROLE FOR EXOCYTOSIS?, Hikima T‚ Lee CR; Vazquez-Cintron, EJ; Ichtchenko K; Rice ME, 9th Annual retreat NYU Neuroscience, New York, USA, Apr. 2016, Poster presentation, False
• Somatodendritic dopamine release: Is D2 autoregulation self-regulation?, Takuya HIKIMA, NYU Neuroscience Meeting, New York, USA, 09 Mar. 2016, Oral presentation, False
• Awakening of presynaptically silent synapses by increasing the size of readily releasable pool, Hikima T‚ Arbuthnott, 6th Special Conference of T International Society for Neurochemistry, Tokyo Japan, Sep. 2014, Poster presentation, True
• Comparison of the characteristics of two different fluorescent probes for neurotransmitter release, Hikima T‚ Arbuthnott, The 37th Annual Meeting of the Japan Neuroscience Society, Yokohama, Jul. 2014, Poster presentation, False
• PKA-dependent activation of presynaptically silent cortical synapses using a fluorescent probe, Takuya HIKIMA; Arbuthnott G, Neuroscience 2013, San Diego, USA, Nov. 2013, Poster presentation, True
• Evidence for the activation of presynaptically silent cortical synapses using a fluorescent probe, Program, Takuya HIKIMA; Arbuthnott G, Neuroscience 2012, New Orleans, USA, Oct. 2012, Poster presentation, True
• Fluorescent pH reporter measurements of vesicular release from terminals of cortical neurons, Takuya HIKIMA; Arbuthnott G, 8th FENS Forum of Neuroscience, Barcelona, Spain, 2012, Poster presentation, True
• Evaluation of activating presynaptically silent synapses using fluorescent pH reporter measurements, Takuya HIKIMA; Arbuthnott G, The 35th Annual Meeting of the Japan Neuroscience Society, Nagoya, Japan, 2012, Poster presentation, False
• Synaptic vesicle dynamics and its plasticity, Hikima T‚Araki; R‚Ishizuka T‚Yawo H, 87th Annual meeting of the Physiological Society of Japan, Morioka, 25 May 2010, Invited oral presentation, False
• Synaptic vesicle dynamics in hippocampus and striatum, Takuya HIKIMA; Garcia-Munoz M; Arbuthnott G, 10th International Basal Ganglia Society Meeting, Long Branch NJ, USA, 2010, Poster presentation, True
• Photocurrent attenuation by Glu97Ala mutation of channelrhodopsin-2, Sugiyama Y; Wang H; Takuya HIKIMA; Sato M; Takahashi T; Kuroda J; Ishizuka T, Yawo, The 86th Annual Meeting of the Physiological Society of Japan, Kyoto, 2009, Poster presentation, False
• Presynaptic dynamics and their modulation by PKC, Yawo H. Takuya; HIKIMA. Suyama; S. Sakagami; H. Ishizuka, The 85th Annual Meeting of the Physiological Society of Japan, Tokyo, 2008, Oral presentation, False
• PKC-dependent reorganization of vesicular dynamics during presynaptic unsilencing, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, The 85th Annual Meeting of the Physiological Society of Japan, Tokyo, 2008, Poster presentation, False
• Phorbol esters-induced reorganization of vesicular dynamics at the hippocampal mossy fiber terminals, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, Neuroscience 2008, Washington DC, USA, 2008, Poster presentation, True
• Phorbol esters-induced presynaptic plasticity at the hippocampal mossy fiber terminals, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, the 1st Brain science summer retreat in Mathushima, Miyagi,, 2008, Poster presentation, False
• Molecular Determinant of Channelrhodopsin Photocurrent, Wang H; Sugiyama Y; Takuya HIKIMA; Takahashi T; Ishizuka T; Yawo H, neuroscience Workshop for Young Scientist, Shanghai, China, 2008, Poster presentation, True
• Optical analysis of PKC-dependent modulation at mossy fiber terminals of hippocampus using synaptopHluorin transgenic mice, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, The 84th Annual Meeting of the Physiological Society of Japan, Osaka,, 2007, Poster presentation, False
• Optical analysis of PKC-dependent modulation at mossy fiber terminals of hippocampus using mice genetically-expressing synaptopHluorin, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, 7th IBRO World Congress of Neuroscience, Melbourne, Australia, 2007, Poster presentation, True
• Activation of presynaptically silent synapses -one of underlying mechanisms enhancing mossy fiber transmission in the hippocampus, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, The 30th Annual Meeting of the Japan Neuroscience Society, Yokohama, 2007, Poster presentation, False
• Neurotransmission fidelity at hippocampal mossy fiber-CA3 synapses, Program, Yawo; H. Suyama S; Takuya HIKIMA; Sakagami H; Ishizuka T, The 40th Tohoku Physiological Meeting, Sendai, 2007, Oral presentation, False
• Quantitative imaging of exo-endocytosis at mossy fiber presynaptic terminals of hippocampus by genetically expressed fluorescent probe, Takuya HIKIMA; Araki R; Ishizuka T; Yawo H, The 29th Annual Meeting of the Japan Neuroscience Society, 2006, Poster presentation, False
• Measurement and stimulus technology of neuronal function using light for analysis of neuronal network, Ishizuka T; Araki R; Takuya HIKIMA; Kakuta M; Suzuki S; Yawo, H, Measurement and stimulus technology of neuronal function using light for analysis of neuronal network, Sendai, 2006, Oral presentation, False
• Optimal measurement of exocytosis using synapto-pHluorin transgenic mice, Araki R; Sakagami H; Yanagawa Y; Takuya HIKIMA; Ishizuka; T. Yawo, Neuroscience 2005, Washington DC, USA, 2005, Poster presentation, True

Social contributions

Social Contribution

• Marlene and Paolo Fresco I nstitute for Par kinson’s and Movem ent ,, Marlene and Paolo Fresco Foundation, Dec. 2016
• OIST science talk ( high school students), OIST, Sep. 2014
• OIST science talk ( high school students), OIST, Jul. 2014
• OIST educational course to children, OIST educational course to children, Jul. 2014
• Mar. 2014
• OIST Open campus, OIST, Oct. 2009