KOBAYASHI ERI

Profiles

Profiles

• 氏名

  KOBAYASHI ERI

Affiliation

• Department of Medical Genome Science, Senior Assistant Professor

Profile and Settings

Alternate Names

• Eri H Kobayashi

Affiliation

• Dokkyo Medical University, Department of Medical Genome Science, Others

Degree

• Doctor of Philosophy in Medical Science, Tohoku University, Mar. 2012

Research Experience

• Jan. 2026, 9999, Dokkyo Medical University, Department of Medical Genome Science, 講師
• Mar. 2020, Dec. 2026, 東北大学, 助教
• Jan. 2017, Jan. 2020, National Institute of Health, Visiting fellow, United States
• Apr. 2012, Dec. 2016, Tohoku University, 医化学分野, 助教

Research achievements

Published Papers

Original paper
• Development of a robust method to derive human trophoblast stem cells from late-gestation placentas and its application to preeclampsia, Akira Oike; Eri H. Kobayashi; Yasuhiro Yamamoto; Hirotaka Hamada; Sota Takahashi; Takanori Shimizu; Akane Kitamura; Asato Sekiya; Norio Kobayashi; Shun Shibata; Shun Endo; Tetsuya Sato; Naoto Kubota; Chie Kikutake; Mikita Suyama; Takahiro Arima; Hiroaki Okae, Proceedings of the National Academy of Sciences, 123(24), 11 Jun. 2026

  DOI
• Glucose-activated JMJD1A drives visceral adipogenesis via α-ketoglutarate-dependent chromatin remodeling, Chenxu Yang; Makoto Arai; Eko Fuji Ariyanto; Ji Zhang; Debby Mirani Lubis; Ryo Ito; Shiyu Xie; Mio Nitta; Fuka Kawashima; Tomofumi Ishitsuka; Chaoran Yang; Tomohiro Suzuki; Tetsuro Komatsu; Hina Sagae; Hitomi Jin; Hiroki Takahashi; Eri Kobayashi; Yuchen Wei; Bohao Liu; Hyunmi Choi; Youichiro Wada; Toshiya Tanaka; Tsuyoshi Osawa; Hiroshi Kimura; Tatsuhiko Kodama; Hiroyuki Aburatani; Makoto Tachibana; Yoichi Shinkai; Takeshi Inagaki; Tomoyoshi Soga; Timothy F. Osborne; Takeshi Yoneshiro; Yoshihiro Matsumura; Juro Sakai, Cell Reports, 44(8), 116060-116060, Aug. 2025

  DOI
• Modeling embryo-endometrial interface recapitulating human embryo implantation, Shun Shibata; Shun Endo; Luis A. E. Nagai; Eri H. Kobayashi; Akira Oike; Norio Kobayashi; Akane Kitamura; Takeshi Hori; Yuji Nashimoto; Ryuichiro Nakato; Hirotaka Hamada; Hirokazu Kaji; Chie Kikutake; Mikita Suyama; Masatoshi Saito; Nobuo Yaegashi; Hiroaki Okae; Takahiro Arima, Science Advances, 10(8), 23 Feb. 2024

  DOI
• Trophoblast stem cell-based organoid models of the human placental barrier., Takeshi Hori; Hiroaki Okae; Shun Shibata; Norio Kobayashi; Eri H Kobayashi; Akira Oike; Asato Sekiya; Takahiro Arima; Hirokazu Kaji, Nature communications, 15(1), 962-962, 08 Feb. 2024

  DOI
• CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development., Takanori Shimizu; Akira Oike; Eri H Kobayashi; Asato Sekiya; Norio Kobayashi; Shun Shibata; Hirotaka Hamada; Masatoshi Saito; Nobuo Yaegashi; Mikita Suyama; Takahiro Arima; Hiroaki Okae, Proceedings of the National Academy of Sciences of the United States of America, 120(51), e2311372120, 19 Dec. 2023

  DOI
• The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells, Norio Kobayashi; Hiroaki Okae; Hitoshi Hiura; Naoto Kubota; Eri H. Kobayashi; Shun Shibata; Akira Oike; Takeshi Hori; Chie Kikutake; Hirotaka Hamada; Hirokazu Kaji; Mikita Suyama; Marie-Line Bortolin-Cavaillé; Jérôme Cavaillé; Takahiro Arima, Nature Communications, 13(1), Dec. 2022

  DOI
• Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability, Robin Sebastian; Eri K. Hosogane; Eric G. Sun; Andy D. Tran; William C. Reinhold; Sandra Burkett; David M. Sturgill; Prabhakar R. Gudla; Yves Pommier; Mirit I. Aladjem; Philipp Oberdoerffer, Molecular Cell, 79(5), 836-845.e7, Sep. 2020

  DOI
• Aryl Hydrocarbon Receptor Directly Regulates Artemin Gene Expression., Tomohiro Edamitsu; Keiko Taguchi; Eri H Kobayashi; Ryuhei Okuyama; Masayuki Yamamoto, Molecular and cellular biology, 39(20), 15 Oct. 2019

  DOI
• Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation., Kenta Kikuchi; Mayumi Iida; Naoki Ikeda; Shigetaka Moriyama; Michito Hamada; Satoru Takahashi; Hiroshi Kitamura; Takashi Watanabe; Yoshinori Hasegawa; Koji Hase; Takeshi Fukuhara; Hideyo Sato; Eri H Kobayashi; Takafumi Suzuki; Masayuki Yamamoto; Masato Tanaka; Kenichi Asano, Journal of immunology (Baltimore, Md. : 1950), 201(2), 635-651, 15 Jul. 2018

  DOI
• Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions., Jeongkyu Kim; David Sturgill; Robin Sebastian; Simran Khurana; Andy D Tran; Garrett B Edwards; Alex Kruswick; Sandra Burkett; Eri K Hosogane; William W Hannon; Urbain Weyemi; William M Bonner; Karolin Luger; Philipp Oberdoerffer, Molecular cell, 69(1), 36-47, 04 Jan. 2018

  DOI
• Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus., Takafumi Suzuki; Shiori Seki; Keiichiro Hiramoto; Eriko Naganuma; Eri H Kobayashi; Ayaka Yamaoka; Liam Baird; Nobuyuki Takahashi; Hiroshi Sato; Masayuki Yamamoto, Nature communications, 8, 14577-14577, 24 Feb. 2017

  DOI
• A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways., Liam Baird; Tadayuki Tsujita; Eri H Kobayashi; Ryo Funayama; Takeshi Nagashima; Keiko Nakayama; Masayuki Yamamoto, Molecular and cellular biology, 37(4), 15 Feb. 2017

  DOI
• The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin., Takanori Hidaka; Eisaku Ogawa; Eri H Kobayashi; Takafumi Suzuki; Ryo Funayama; Takeshi Nagashima; Taku Fujimura; Setsuya Aiba; Keiko Nakayama; Ryuhei Okuyama; Masayuki Yamamoto, Nature immunology, 18(1), 64-73, Jan. 2017

  DOI
• Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription., Eri H Kobayashi; Takafumi Suzuki; Ryo Funayama; Takeshi Nagashima; Makiko Hayashi; Hiroki Sekine; Nobuyuki Tanaka; Takashi Moriguchi; Hozumi Motohashi; Keiko Nakayama; Masayuki Yamamoto, Nature communications, 7, 11624-11624, 23 May 2016

  DOI
• Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of a GATA1 Protein Lacking the N-terminal Domain, Eri Kobayashi; Ritsuko Shimizu; Yuko Kikuchi; Satoru Takahashi; Masayuki Yamamoto, JOURNAL OF BIOLOGICAL CHEMISTRY, 285(1), 773-783, Jan. 2010

  DOI

Review paper
• Genomic imprinting in human placentation., Eri H Kobayashi; Shun Shibata; Akira Oike; Norio Kobayashi; Hirotaka Hamada; Hiroaki Okae; Takahiro Arima, Reproductive medicine and biology, 21(1), e12490, Dec. 2022

  DOI
• 生殖医学研究の最前線-進歩し続ける基礎研究- 疾患特異的ヒト胎盤幹細胞の樹立, 岡江 寛明; 清水 孝規; 遠藤 俊; 大池 輝; 小林 記緒; 柴田 峻; 小林 枝里; 有馬 隆博, 日本生殖医学会雑誌, 66(4), 227-227, Oct. 2021
• 【ヒト胎盤機能と病態】ヒト栄養膜幹細胞と病態 疾患の病態モデル, 小林 枝里; 岡江 寛明; 有馬 隆博, HORMONE FRONTIER IN GYNECOLOGY, 28(3), 213-218, Sep. 2021
• Unique features and emerging in vitro models of human placental development, Shun Shibata; Eri H. Kobayashi; Norio Kobayashi; Akira Oike; Hiroaki Okae; Takahiro Arima, Reproductive Medicine and Biology, 19(4), 301-313, Oct. 2020

  DOI
• 【酸化ストレスとその防御】表皮の酸化ストレスとその防御機構, 小林 枝里; 日高 高徳; 山本 雅之, FRAGRANCE JOURNAL, 41(2), 16-20, Feb. 2013
• Roles nrf2 plays in myeloid cells and related disorders., Eri Kobayashi; Takafumi Suzuki; Masayuki Yamamoto, Oxidative medicine and cellular longevity, 2013, 529219-529219, 2013

  DOI

MISC

• 【図説 産婦人科医のための臨床遺伝学必修知識I】知っておきたいエピゲノムの基礎知識, 柴田 峻; 小林 枝里; 有馬 隆博, 産婦人科の実際, 72(8), 781-786, Aug. 2023
• 妊娠高血圧症候群における細胞性栄養膜細胞を用いたマルチオミックス解析, 遠藤俊; 遠藤俊; 柴田峻; 小林枝里; 清水孝規; 清水孝規; 大池輝; 小林記緒; 岡江寛明; 濱田裕貴; 齋藤昌利; 有馬隆博; 八重樫伸生, 日本絨毛性疾患研究会・日本胎盤学会学術集会プログラム・抄録集, 40th-30th (CD-ROM), 2022
• Establishment of Placental disease models by human TS cells, 大池輝; 小林枝里; 小林記緒; 柴田峻; 岡江寛明; 北村茜; 宮内尚子; 有馬隆博, Bio Clinica, 36(5), 2021
• AhRによる神経栄養因子アルテミンの発現誘導が惹起するアトピー性皮膚炎の痒み過敏, 枝光智大; 枝光智大; 田口恵子; 小林枝里; 奥山隆平; 山本雅之, 日本生化学会大会(Web), 91st, 2018
• Mafによる組織マクロファージの形質変化, 浅野謙一; 菊池健太; 飯田真弓; 池田直輝; 森山誉隆; 濱田理人; 高橋智; 北村浩; 渡辺貴志; 長谷川嘉則; 長谷耕二; 福原武志; 佐藤英世; 小林枝里; 鈴木隆史; 山本雅之, 日本Cell Death学会学術集会プログラム抄録集, 27th, 2018
• 生体防御因子Nrf2の遺伝的および薬剤誘導的活性化は多発性硬化症の症状を改善する, 林真貴子; 森口尚; 森口尚; 鈴木未来子; 鈴木未来子; 小林枝里; 山本雅之; 山本雅之, 日本生化学会大会(Web), 89th, ROMBUNNO.2T17‐06(2P‐362) (WEB ONLY)-362)], 2016
• Aryl hydrocarbon receptor activation at keratinocyte leads to atopic dermatitis-like lesion via artemin induction, T. Hidaka; E. Ogawa; E. Kobayashi; T. Suzuki; T. Fujimura; S. Aiba; R. Okuyama; M. Yamamoto, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 135, S2-S2, Sep. 2015