OKUDA TATSUYA

Profiles

Profiles

• 氏名

  OKUDA TATSUYA

Affiliation

• Department of Fundamental Education, Associate Professor

Profile and Settings

Affiliation

• Dokkyo Medical University, Chemistry Section, Department of Fundamental Education, Premedical Sciences, Associate Professor, Associate prof lecturer lv

Degree

• 31 Mar. 2004
• 31 Mar. 2001

Research Experience

• 01 Feb. 2010, 31 Mar. 2014, Kyushu University, Institute for Materials Chemistry and Engineering, Assistant Professor, Japan
• 01 Jan. 2007, 31 Jan. 2010, Kyushu University, Institute for Materials Chemistry and Engineering, Postdoctoral Fellow, Japan
• 01 Oct. 2004, 31 Dec. 2006, Japan Association for the Advencement of Medical Equipment, Postdoctoral Fellow
• 01 Apr. 2004, 30 Sep. 2004, Kyoto University, Faculty of Pharmaceutical Sciences, Postdoctoral Fellow, Japan

Education

• 01 Apr. 2001, 31 Mar. 2004, Nagasaki University, Japan
• 01 Apr. 1999, 31 Mar. 2001, Nagasaki University, Graduate School of Engineering, Japan
• 01 Apr. 1995, 31 Mar. 1999, Nagasaki University, Faculty of Engineering, Department of Applied Chemistry, Japan

Research achievements

Published Papers

Original paper
• Development of PEGylated Cysteine-Modified Lysine Dendrimers with Multiple Reduced Thiols To Prevent Hepatic Ischemia/Reperfusion Injury., Katsumi Hidemasa;Nishikawa Makiya;Hirosaki Rikiya;Okuda Tatsuya;Kawakami Shigeru;Yamashita Fumiyoshi;Hashida Mitsuru;Sakane Toshiyasu;Yamamoto Akira, Molecular pharmaceutics, 13(8), 2867-2873, 2016

  DOIPermalink
• S/O-nanodispersion electrospun fiber mesh effective for sustained release of healthy plasmid DNA with the structural and functional integrity., Okuda Tatsuya;Tahara Yoshiro;Kamiya Noriho;Goto Masahiro;Kidoaki Satoru, Journal of biomaterials science. Polymer edition, 24(10), 1277-1290, 2013

  DOIPermalink
• Formation of nanoporous fibers by the self-assembly of a pyromellitic diimide-based macrocycle., Nakagaki Takeshi;Harano Aya;Fuchigami Yoko;Tanaka Eishi;Kidoaki Satoru;Okuda Tatsuya;Iwanaga Tetsuo;Goto Kenta;Shinmyozu Teruo, Angewandte Chemie (International ed. in English), 49(50), 9676-9679, 10 Dec. 2010

  DOIPermalink
• Time-programmed dual release formulation by multilayered drug-loaded nanofiber meshes., Okuda Tatsuya;Tominaga Kengo;Kidoaki Satoru, Journal of controlled release : official journal of the Controlled Release Society, 143(2), 258-264, 19 Apr. 2010

  DOIPermalink
• Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells., Shigeta Kosuke;Kawakami Shigeru;Higuchi Yuriko;Okuda Tatsuya;Yagi Hiroko;Yamashita Fumiyoshi;Hashida Mitsuru, Journal of controlled release : official journal of the Controlled Release Society, 118(2), 262-270, 02 Apr. 2007

  DOIPermalink
• PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice., Okuda Tatsuya;Kawakami Shigeru;Akimoto Naomi;Niidome Takuro;Yamashita Fumiyoshi;Hashida Mitsuru, Journal of controlled release : official journal of the Controlled Release Society, 116(3), 330-336, 01 Dec. 2006

  DOIPermalink
• Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration., Okuda Tatsuya;Kawakami Shigeru;Maeie Tadahiro;Niidome Takuro;Yamashita Fumiyoshi;Hashida Mitsuru, Journal of controlled release : official journal of the Controlled Release Society, 114(1), 69-77, 10 Aug. 2006

  DOIPermalink
• Long circulation of intravenously administered plasmid DNA delivered with dendritic poly(L-lysine) in the blood flow., Kawano Takahito;Okuda Tatsuya;Aoyagi Haruhiko;Niidome Takuro, Journal of controlled release : official journal of the Controlled Release Society, 99(2), 329-337, 30 Sep. 2004

  DOIPermalink
• Cytosolic soluble proteins induce DNA release from DNA--gene carrier complexes., Okuda Tatsuya;Niidome Takuro;Aoyagi Haruhiko, Journal of controlled release : official journal of the Controlled Release Society, 98(2), 325-332, 11 Aug. 2004

  DOIPermalink
• Characters of dendritic poly(L-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro., Okuda Tatsuya;Sugiyama Akiko;Niidome Takuro;Aoyagi Haruhiko, Biomaterials, 25(3), 537-544, Feb. 2004

  DOIPermalink
• Gangliosides act as co-receptors for Salmonella enteritidis FliC and promote FliC induction of human beta-defensin-2 expression in Caco-2 cells., Ogushi Ken-ichi;Wada Akihiro;Niidome Takuro;Okuda Tatsuya;Llanes Rafael;Nakayama Masaaki;Nishi Yoshito;Kurazono Hisao;Smith Kelly D;Aderem Alan;Moss Joel;Hirayama Toshiya, The Journal of biological chemistry, 279(13), 12213-12219, 26 Mar. 2004

  DOIPermalink
• Time-dependent complex formation of dendritic poly(L-lysine) with plasmid DNA and correlation with in vitro transfection efficiencies., Okuda Tatsuya;Kidoaki Satoru;Ohsaki Mio;Koyama Yoshiyuki;Yoshikawa Kenichi;Niidome Takuro;Aoyagi Haruhiko, Organic & biomolecular chemistry, 1(8), 1270-1273, 21 Apr. 2003

  DOIPermalink
• Novel poly(ethylene glycol) derivatives having carboxylic acid pendant groups: syntheses and their protection and enhancing effect on non-viral transfection systems, Koyama Y, Ito T, Matsumoto H, Tanioka A, Okuda T, Aoyagi H, Niidome T, Journal of biomaterials science. Polymer edition, 6(14), 515-531, 2003

  DOI
• In vitro gene transfection using dendritic poly(L-lysine)., Ohsaki Mio;Okuda Tatsuya;Wada Akihiro;Hirayama Toshiya;Niidome Takuro;Aoyagi Haruhiko, Bioconjugate chemistry, 13(3), 510-517, 2002

  DOIPermalink

Review paper
• Multidrug delivery systems with single formulation ~current status and future perspective~, Okuda T, Kidoaki S, Journal of Biomaterials and Nanobiotechnology, 1(3), 50-60, 2012

  DOI
• Development of time-programmed dual release system using multi-layered fiber mesh sheet by sequential electrospinning, Okuda T, KidoakiS, Journal of Robotics and Mechatronics, 5(22), 579-586, 20 Oct. 2010

  DOI

University administration

学内委員会等活動

• 2021
• 2020
• 2017