Researchers Database

UETA HISASHI

Position: Associate Professor
Last Updated :2025/04/28

Profiles

Profiles

  • 氏名

    UETA HISASHI

Affiliation

  • Associate Professor

Profile and Settings

Degree

  • Ph.D (Eng), Tokushima University, Faculty of Engineering, 01 Sep. 2004
  • 24 Feb. 2009

Research Interests

  • dendritic-cell, transplant immunology, exsosome, lymph, cellular vaccine

Research Experience

  • 01 Apr. 2021, Dokkyo Medical University, Department of Anatomy, Associate Professor, Japan
  • 01 Apr. 2017, 31 Mar. 2021, Dokkyo Medical University, Department of Anatomy (Macro), Associate Professor, Japan
  • 01 May 2013, 30 Apr. 2014, Massachusetts General Hospital, Center for Immunology and Inflammatory Diseases, Visiting Researcher, United States

Committee Memberships

  • 01 Jan. 2023, 31 Dec. 2026
  • 27 Mar. 2020

Research achievements

Awards

  • 22 Apr. 2021, International Immunology, Editor's Choice, Suppression of liver transplant rejection by anti-donor MHC antibodies via depletion of donor immunogenic dendritic cells., Author, Official journal
  • 2020, Author, Japan society
  • 2020, Japan Society of Immunology, Best Presentation Award, Novel DC targeting by allogenic T-cells for multifocal prophylactic antibody production, Ueta H, Kitazawa Y, Sawanobori Y, Katakai T, Ueha S, Matsushima K, Tokuda N, Matsuno K, Author, Japan society
  • 2019, Dokkyo Medical Fundation, Representative of Institution, Publisher
  • 2018, International Immunology, Editor's Choice, Rapid immunosurveillance by recirculating lymphocytes in the rat intestine: critical role of unsulfated sialyl-Lewis X on high endothelial venules of the Peyer's patches., Uchida T*, Ueta H*, Xu XD, Hirakawa J, Tahara K, Zhou S, Sawanobori Y, Simmons S, Kitazawa Y, Kawashima H, Matsuno K, Author, Publisher
  • 22 Mar. 2023, Representative of Institution, Others
  • 15 May 2023, Representative of Institution

Published Papers

    Original paper
  • Extracellular ATP limits homeostatic T cell migration within lymph nodes, Kobayashi D, Sugiura Y, Umemoto E, Takeda A, Ueta H, Hayasaka H, Matsuzaki S, Katakai T, Suematsu M, Hamachi I, Yegutkin GG, Salmi M, Jalkanen S, Miyasaka M, Frontiers in Immunology, 22 Dec. 2021
  • Selective involution of thymic medulla by cyclosporine A with a decrease of mature thymic epithelia, XCR1+ dendritic cells, and epithelium-free areas containing Foxp3 + thymic regulatory T cells, Yasushi Sawanobori, Yusuke Kitazawa, Hisashi Ueta, Kenjiro Matsuno, Nobuko Tokuda, Histochemistry and Cell Biology, 16 May 2021
  • Suppression of liver transplant rejection by anti-donor MHC antibodies via depletion of donor immunogenic dendritic cells., Ueta H, Xu XD, Yu B, Kitazawa Y, Yu E, Hara Y, Morita-Nakamura M, Zhou S, Sawanobori Y, Ueha S, Rokutan K, Tanaka T, Tokuda N, Matsushima K, Matsuno K, International Immunology, 33(5), 261-272, 22 Apr. 2021
  • Monotherapy With Anti-CD70 Antibody Causes Long-Term Mouse Cardiac Allograft Acceptance With Induction of Tolerogenic Dendritic Cells., Zhao Jing;Que Weitao;Du Xiaoxiao;Fujino Masayuki;Ichimaru Naotsugu;Ueta Hisashi;Tokuda Nobuko;Guo Wen-Zhi;Zabrocki Piotr;de Haard Hans;Nonomura Norio;Li Xiao-Kang, Frontiers in Immunology, 11, 555996, 19 Feb. 2021
  • Novel Targeting to XCR1+ Dendritic Cells Using Allogeneic T Cells for Polytopical Antibody Responses in the Lymph Nodes., Kitazawa Yusuke;Ueta Hisashi;Sawanobori Yasushi;Katakai Tomoya;Yoneyama Hiroyuki;Ueha Satoshi;Matsushima Kouji;Tokuda Nobuko;Matsuno Kenjiro, Frontiers in Immunology, 10, 1195, 29 May 2019
  • Visualizing the Rapid and Dynamic Elimination of Allogeneic T Cells in Secondary Lymphoid Organs., Kanda Yasuhiro;Takeuchi Arata;Ozawa Madoka;Kurosawa Yoichi;Kawamura Toshihiko;Bogdanova Dana;Iioka Hidekazu;Kondo Eisaku;Kitazawa Yusuke;Ueta Hisashi;Matsuno Kenjiro;Kinashi Tatsuo;Katakai Tomoya, Journal of Immunology (Baltimore, Md. : 1950), 201(3), 1062-1072, 01 Aug. 2018
  • Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen., Ueta Hisashi;Kitazawa Yusuke;Sawanobori Yasushi;Ueno Takamasa;Ueha Satoshi;Matsushima Kouji;Matsuno Kenjiro, International immunology, 30(2), 53-67, 08 May 2018
  • Rapid immunosurveillance by recirculating lymphocytes in the rat intestine: critical role of unsulfated sialyl-Lewis X on high endothelial venules of the Peyer's patches., Uchida Tomomi;Ueta Hisashi;Xu Xue-Dong;Hirakawa Jotaro;Tahara Kazunori;Zhou Shu;Sawanobori Yasushi;Simmons Szandor;Kitazawa Yusuke;Kawashima Hiroto;Matsuno Kenjiro, International immunology, 30(1), 23-33, 03 Feb. 2018
  • Anatomical basis for simultaneous block of greater and third occipital nerves, with an ultrasound-guided technique., Kariya Ken;Usui Yosuke;Higashi Naoko;Nakamoto Tatsuo;Shimbori Hironobu;Terada Satoshi;Takahashi Hideo;Ueta Hisashi;Kitazawa Yusuke;Sawanobori Yasushi;Okuda Yasuhisa;Matsuno Kenjiro, Journal of anesthesia, 32(4), 483-492, 2018
  • Graft-Versus-Host Disease Following Liver Transplantation: Development of a High-Incidence Rat Model and a Selective Prevention Method., Yu E*, Ueta H*, Kimura H, Kitazawa Y, Sawanobori Y, Matsuno K, American Journal of Transplantation, 17(4), 979-991, Apr. 2017
  • Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria., Hirako IC, Ataide MA, Faustino L, Assis PA, Sorensen EW, Ueta H, Araujo NM, Menezes GB, Luster AD, Gazzinelli RT, Nature Communication, 7, 13277, 03 Nov. 2016
  • Direct evidence for activated CD8+ T cell transmigration across portal vein endothelial cells in liver graft rejection., Kariya Taro;Ueta Hisashi;Xu Xue-Dong;Koga Daisuke;Ezaki Taichi;Yu Enqiao;Kusumi Satoshi;Kitazawa Yusuke;Sawanobori Yasushi;Ushiki Tatsuo;Issekutz Thomas;Matsuno Kenjiro, Journal of Gastroenterology, 51(10), 985-998, Oct. 2016
  • Expression of area-specific M2-macrophage phenotype by recruited rat monocytes in duct-ligation pancreatitis., Yu Enqiao;Goto Mataro;Ueta Hisashi;Kitazawa Yusuke;Sawanobori Yasushi;Kariya Taro;Sasaki Masaru;Matsuno Kenjiro, Histochemistry and Cell Biology, 145(6), 659-673, Jun. 2016
  • Pivotal role of duct epithelia in salivary gland GVHD., Sasaki M, Sawanobori S, Tanaka T, Kikuta, Ueta H, Kitazawa Y, Matsuno K, Arch Histol Cytol., 76(1), 1-8, Jan. 2016
  • A novel multicolor immunostaining method using ethynyl deoxyuridine for analysis of in situ immunoproliferative response., Kitazawa Y, Ueta H, Hunig T, Sawanobori Y, Matsuno K, Histochemistry and Cell Biology, 144(3), 195-208, Sep. 2015
  • Three distinct subsets of thymic epithelial cells in rats and mice defined by novel antibodies., Sawanobori Y, Ueta H, Dijkstra CD, Park CG, Satou M, Kitazawa Y, Matsuno K, PLoS ONE, 9(10), e109995, Oct. 2014
  • Role of uterine contraction in regeneration of the murine postpartum endometrium., Yoshii A, Kitahara S, Ueta H, Matsuno K, Ezaki T, Biol Reprod., 91(2), 32, Sep. 2014
  • Two immunogenic passenger dendritic-cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities., Yu B*, Ueta H*, Kitazawa Y, Tanaka T, Adachi K, Kimura H, Morita M, Sawanobori Y, Qian HX, Kodama T, Matsuno K, Hepatology., 56(4), 1532-1545, Oct. 2012
  • Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals., Park CG, Rodriguez A, Ueta H, Lee H, Pack M, Matsuno K, Steinman RM, J Immunol Methods., 377(1-2), 15-22, Mar. 2012
  • Utility of nano-sized, water-in-oil emulsion as a sustained release formulation of glycyrrhizin., Koga K, Nishimon Y, Ueta H, Matsuno K, Takada K, Biol Pharm Bull., 34(2), 300-305, 2011
  • Simultaneous immunohistochemical detection of gangliosides and neuronal markers in paraformaldehyde-fixed nervous tissues by acetone etching., Sakumoto Y, Ueta H, Yuki N, Matsuno K., Arch Histol Cytol., 72(2), 77-90, Jul. 2009
  • Systemic transmigration of allosensitizing donor dendritic cells to host secondary lymphoid organs after rat liver transplantation., Ueta H, Shi C, Miyanari N, Xu XD, Zhou S, Yamashita M, Ezaki T, Matsuno K, Hepatology., 47(4), 1352-1362, Apr. 2008
  • Trafficking of recirculating lymphocytes in the rat liver: rapid transmigration into the portal area and then to the hepatic lymph., Xu XD, Ueta H, Zhou S, Shi C, Koga D, Ushiki T, Matsuno K, Liver Int., 28(3), 319-330, Mar. 2008
  • Predominant donor CD103+CD8+ T cell infiltration into the gut epithelium during acute GvHD: a role of gut lymph nodes., Zhou S, Ueta H, Xu XD, Shi C, Matsuno K, Int Immunol., 20(3), 385-394, Mar. 2008
  • Localization of enolase in synaptic plasma membrane as an alphagamma heterodimer in rat brain., Ueta H, Nagasawa H, Oyabu-Manabe Y, Toida K, Ishimura K, Hori H., Neurosci Res., 48(4), 379-386, Apr. 2004
  • Temporal and spatial dynamics of immune cells in spontaneous liver transplant tolerance., Que W, Ueta H, Hu X, Morita-Nakagawa M, Fujino M, Ueda D, Tokuda N, Huang W, Guo WZ, Zhong L, Li XK., iScience, 26(9), 2023
    Review paper
  • 78(6), 744-750, Jun. 2019
  • 37(10), 1088-1091, Oct. 2017
  • 49(4), 161-164, Apr. 2017
  • 259(5), 453-458, Oct. 2016
  • Preventing rejection of transplanted organs through the morphology-based microenvironment research., H.Ueta, N.Tokuda, Acta Anatomica Nipponica, 99(1), 7-10, Mar. 2024
    Other
  • 47(2), Jul. 2020
  • A New Multicolor Immunostaining Method for analysis of Immunoproliferative Response, Kitazawa Y, Ueta H, Sawanobori Y, Yu E, Kariya T, Sasaki M, Uchida T, Kariya K, Sakumoto J, Sasaki K, Yamada Y, Matsund K, Dokkyo Journal of Medical Sciences, 43((1)), 91-103, Mar. 2016
  • The Immunotherapy mediated by Dendritic-Cells, Matsuno K, Ueta H, Sawanobori Y, Kitazawa Y, Yu E, Dokkyo Journal of Medical Sciences, 41((3)), 245-255, 2014
  • Migration pathways for graft-derived dendritic-cell subsets after rat liver transplantation, Ueta H, Yu B, Matsuno K, Japanese Journal of Lymphology, 36((1)), 18-22, Jun. 2013
  • 47((1)), 33-37, 2012
  • The microstructure of secondary lymphoid organs that support immune cell trafficking., Matsuno K, Ueta H, Shu Z, Xue-Dong X, Sawanobori Y, Kitazawa Y, Bin Y, Yamashita M, Shi C, Arch Histol Cytol., 73(1), 1-21, 2010
  • Trafficking and role of dendritic cells in the liver, Ueta H, Matsuno K, KAN TAN SUI, 58((2)), 193-199, Apr. 2009
  • 32((2)), 63-66, 2009
  • 9, 63-67, 2008
  • Liver DC, functional subsets and trafficking, Ueta H, Matsuno K, Experimental Medicine, 26((20)), 121-127, 2008
  • Localization and trafficking of immunocompetent cells, Ueta H, Matsuno K, KAN TAN SUI, 52((4)), 499-508, Apr. 2006
  • 13((4)), 413-418, 2005
  • 37((13)), 550-554, 2005

Books etc

  • Introduction to the Human Body, Contributor, Gerard J. Tortora, Bryan Derrickson, 30 Aug. 2020, 670, 434-461, Not refereed, Japanese, Textbook, Domestic journal, 978-4-621-30539-3
  • Joint translation, Nov. 2018, 289-318, 978-4-621-30339-9

Presentations

  • Suppression of hepatic allograft rejection by depleting donor immunogenic dendritic cells: implication of donor-specific transfusion, Ueta H, Kitazawa Y, Sawanobori Y, Matsuno K, Tokuda N, 08 Dec. 2021, 08 Dec. 2021, 12 Dec. 2021, Poster presentation, Japan Society of Immunology, Japan, False, Domestic journal
  • Transmigration of activated CD8+ T-cell across the portal vein during hepatic allograft rejection, Ueta H, Kariya T, Kitazawa Y, Sawanobori Y, Matsuno K, Dec. 2016, Oral presentation, Japan Society of Immunology, False
  • Area-specific M2-macrophage differentiation by recruited monocytes in rat duct-ligation acute pancreatitis model, Ueta H, Yu E, Goto M, Kitazawa Y, Sawanobori Y, Matsuno K, Jun. 2016, Poster presentation, International Symposium on Molecular Cell Biology of Macrophages, False
  • Role of lymph-derived extracellular vesicles and area-specific Foxp3+ cells in the pathogenesis of Ulcerative Colitis, Hisashi Ueta, Mina Shirabe, Yusuke Kitazawa, Yasushi Sawanobori, Nobuko Tokuda, 22 Mar. 2024, 21 Mar. 2024, 23 Mar. 2024, Oral presentation, False, Domestic journal
  • Role of niche-specific Foxp3+ cell and lymph extracellular vesicles in the pathogenesis of Ulcerative Colitis, Hisashi Ueta, Toshiya Tanaka, Hidefumi Kojima, Keiichi Tominaga, Yusuke Kitazawa, Yasushi Sawanobori, Mina Shirabe, Atsushi Irisawa, Nobuko Tokuda, 19 Jan. 2024, 17 Jan. 2024, 19 Jan. 2024, Poster presentation

学内助成金

  • 01 Apr. 2023, 31 Mar. 2024, 1000000
  • 01 Apr. 2021, 31 Mar. 2022, 1000000
  • 01 Apr. 2019, 31 Mar. 2021, 2000000
  • 01 Apr. 2012, 31 Mar. 2013, 1000000
  • 01 Apr. 2008, 31 Mar. 2009, 1000000

Industrial Property Rights

  • Patent right, 特願2020-536906, 14 Feb. 2020, 特許第6884450号, 14 May 2021, 14 May 2021
  • Patent right, 特願2016-511659, 02 Apr. 2015, 特許第6613412, 15 Nov. 2019

Educational activity

教育活動上特質すべき事項

  • 2018, 2021
  • 16 May 2022

FD活動

  • 2017

Social contributions

Academic Contribution

  • 01 Apr. 2019, 31 Mar. 2026, Not contributing to international academic

Media Coverage

  • Others, Other than myself, 28 Jul. 2021

University administration

学内委員会等活動

  • 2022
  • 2022
  • 2021, 2023
  • 2019, 2021


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