Researchers Database

KAWASE OSAMU

Affiliation: Department of Fundamental Education
Position: Associate Professor
Last Updated :2025/04/28

Profiles

Profiles

  • 氏名

    KAWASE OSAMU

Affiliation

  • Department of Fundamental Education, Associate Professor

Profile and Settings

Degree

  • 31 Mar. 2005

Research Interests

  • reproduction
  • proteomics
  • starfish
  • earthworm
  • black soldier fly
  • sika deer
  • antisperm antibody
  • yolk protein

Research Areas

  • Life Science, Cell biology
  • Life Science, Developmental biology
  • Life Science, Animal life science

Research Experience

  • Apr. 2023, 9999, Dokkyo Medical University, 基本医学, 准教授, Japan
  • Apr. 2014, Mar. 2023, 獨協医科大学, 基本医学, 講師
  • Apr. 2012, Mar. 2014, 獨協医科大学, 基本医学, 助教
  • Aug. 2009, Mar. 2012, 南三陸町役場, 自然環境活用センター, 任期付研究員
  • Apr. 2008, Jul. 2009, 帯広畜産大学, 大動物特殊疾病研究センター, 助教
  • Apr. 2006, Mar. 2008, Obihiro University of Agriculture and Veterinary Medicine, 原虫病研究センター, 博士研究員
  • Apr. 2005, Mar. 2006, Cornell University, College of Veterinary Medicine, Postdoctoral Researcher, United States

Education

  • Apr. 2002, Mar. 2005, 慶應義塾大学大学院, 理工学研究科, 後期博士課程
  • Apr. 2000, Mar. 2002, 慶應義塾大学大学院, 理工学研究科, 前期博士課程
  • Mar. 2000, 慶應義塾大学, 理工学部, 応用化学科

Research achievements

Awards

  • Mar. 2008, 日本獣医学会, 第145回日本獣医学会学術集会大会長賞, トキソプラズマ原虫におけるカルシウム依存的 分泌タンパク質の網羅的同定および動態解析, 川瀬摂;西川義文;神繁樹;李應具;玄学南

Published Papers

    Original paper
  • Characterization of anti-erythrocyte and anti-platelet antibodies in hemolytic anemia and thrombocytopenia induced by Plasmodium spp. and Babesiaspp. infection in mice., Mo Zhou; Jun Xie; Osamu Kawase; Yoshifumi Nishikawa; Shengwei Ji; Shanyuan Zhu; Shinuo Cao; Xuenan Xuan, Frontiers in cellular and infection microbiology, 13, 1143138-1143138, 2023
  • Protozoan and Rickettsial Pathogens in Ticks Collected from Infested Cattle from Turkey, Shengwei Ji; Onur Ceylan; Zhuowei Ma; Eloiza May Galon; Iqra Zafar; Hang Li; Yae Hasegawa; Mutlu Sevinc; Tatsunori Masatani; Aiko Iguchi; Osamu Kawase; Rika Umemiya-Shirafuji; Masahito Asada; Ferda Sevinc; Xuenan Xuan, Pathogens, 11(5), 500, 22 Apr. 2022
  • Identification of novel yolk ferritins unique to planarians: planarians supply aluminum rather than iron to vitellaria in egg capsules., Osamu Kawase; Hisashi Iwaya; Yoshiya Asano; Hiromoto Inoue; Seiya Kudo; Motoki Sasahira; Nobuyuki Azuma; Daisuke Kondoh; Madoka Ichikawa-Seki; Xuenan Xuan; Kimitoshi Sakamoto; Hikaru Okamoto; Hinaki Nakadate; Wataru Inoue; Ikuma Saito; Miyu Narita; Kiyono Sekii; Kazuya Kobayashi, Cell and tissue research, 386(2), 391-413, 28 Jul. 2021
  • Breeding of the endangered dragonfly, Polycanthagyna melanictera, in the artificial pond in the woods of Dokkyo Medical University, 吉野 圭亮; 小笠原 健; 鷲尾 高志; 猪又 光太郎; 村井 陸; 永野律郎; 山口 雄太郎; 川瀬 摂, Annual report of premedical sciences, (11), 103-106, 2021
  • Survey of marine mollusks in Hiraiso coast, Ibaraki prefecture, 島本 和季; 島野 浩樹; 山口 雄輝; 川瀬 摂, Annual report of premedical sciences, (11), 107-110, 2021
  • Detection of sperm-reactive antibodies in wild sika deer and identification of the sperm antigens, Osamu Kawase; Mitsuru Jimbo, JOURNAL OF VETERINARY MEDICAL SCIENCE, 80(5), 802-809, May 2018
  • Immunological Adjuvant Activity of Pectinioside A, the Steroidal Saponin from the Starfish Patiria pectinifera, Osamu Kawase; Osamu Ohno; Kiyotake Suenaga; Xuenan Xuan, NATURAL PRODUCT COMMUNICATIONS, 11(5), 605-606, May 2016
  • Sperm membrane proteome in wild Japanese macaque (Macaca fuscata) and Sika deer (Cervus nippon), Osamu Kawase; Shinuo Cao; Xuenan Xuan, THERIOGENOLOGY, 83(1), 95-102, Jan. 2015
  • Regional Difference of Ray Number Variation in a Starfish, Patiria pectinifera, Osamu Kawase; Ryohei Furukawa, Annual Report of Premedical Sciences, Dokkyo Medical University, 3(3), 49-52, Mar. 2014
  • Seasonality of Gonadal Development in Rare Japanese Brittle Star, Amphiura multispina (Echinodermata, Ophiuroidea, Amphiuridae), Osamu Kawase, Annual Report of Premedical Sciences, Dokkyo Medical University, 2(2), 37-41, Feb. 2013
  • Marine heterogeneous multirobot systems at the great Eastern Japan Tsunami recovery, Robin R. Murphy; Karen L. Dreger; Sean Newsome; Jesse Rodocker; Brian Slaughter; Richard Smith; Eric Steimle; Tetsuya Kimura; Kenichi Makabe; Kazuyuki Kon; Hisashi Mizumoto; Michinori Hatayama; Fumitoshi Matsuno; Satoshi Tadokoro; Osamu Kawase, JOURNAL OF FIELD ROBOTICS, 29(5), 819-831, Sep. 2012
  • Rediscovery and redescription of a rare Japanese brittle star, Amphiura multispina (Echinodermata, Ophiuroidea, amphiuridae), Toshihiko Fujita; Osamu Kawase; Gordon Hendler, Bulletin of the National Museum of Nature and Science. Series A, Zoology, 37(4), 209-215, Dec. 2011
  • Identification of the cross-reactive and species-specific antigens between Neospora caninum and Toxoplasma gondii tachyzoites by a proteomics approach, Houshuang Zhang; Eung-goo Lee; Longzheng Yu; Suguru Kawano; Penglong Huang; Min Liao; Osamu Kawase; Guohong Zhang; Jinlin Zhou; Kozo Fujisaki; Yoshifumi Nishikawa; Xuenan Xuan, PARASITOLOGY RESEARCH, 109(3), 899-911, Sep. 2011
  • Starfish, Asterias amurensis and Asterina pectinifera, as Potential Sources of Th1 Immunity-Stimulating Adjuvants, Osamu Kawase; Youn-Kyoung Goo; Hayato Jujo; Yoshifumi Nishikawa; Xuenan Xuan, JOURNAL OF VETERINARY MEDICAL SCIENCE, 73(2), 227-229, Feb. 2011
  • Characterization of a novel thrombospondin-related protein in Toxoplasma gondii, Osamu Kawase; Yoshifumi Nishikawa; Hiroshi Bannai; Makoto Igarashi; Tomohide Matsuo; Xuenan Xuan, PARASITOLOGY INTERNATIONAL, 59(2), 211-216, Jun. 2010
  • Overproduction of the Pro-Apoptotic Molecule, Programmed Cell Death 5, in Toxoplasma gondii Leads to Increased Apoptosis of Host Macrophages, Hiroshi Bannai; Yoshifumi Nishikawa; Hany Mohamed Ibrahim; Kyoko Yamada; Osamu Kawase; Jun-ichi Watanabe; Chihiro Sugimoto; Xuenan Xuan, JOURNAL OF VETERINARY MEDICAL SCIENCE, 71(9), 1183-1189, Sep. 2009
  • Programmed Cell Death 5 from Toxoplasma gondii: A secreted molecule that exerts a pro-apoptotic effect on host cells, Hiroshi Bannai; Yoshifumi Nishikawa; Tomohide Matsuo; Osamu Kawase; Junichi Watanabe; Chihiro Sugimoto; Xuenan Xuan, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 159(2), 112-120, Jun. 2008
  • Proteomic analysis off calcium-dependent secretion in Toxoplasma gondii, Osamu Kawase; Yoshifumi Nishikawa; Hiroshi Bannai; Houshuang Zhang; Guohong Zhang; Shigeki Jin; Eung-Goo Lee; Xuenan Xuan, PROTEOMICS, 7(20), 3718-3725, Oct. 2007
  • A heterologous prime-boost vaccination regime using DNA and a vaccinia virus, both expressing GRA4, induced protective immunity against Toxoplasma gondii infection in mice, G. Zhang; V. T. T. Huong; B. Battur; J. Zhou; H. Zhang; M. Liao; O. Kawase; E. G. Lee; G. Dautu; M. Igarash; Y. Nishikawa; X. Xuan, PARASITOLOGY, 134, 1339-1346, Sep. 2007
  • Toxoplasma gondii infection induces apoptosis in noninfected macrophages: role of nitric oxide and other soluble factors, Y. Nishikawa; O. Kawase; O. Vielemeyer; H. Suzuki; K. A. Joiner; X. Xuan; H. Nagasawa, PARASITE IMMUNOLOGY, 29(7), 375-385, Jul. 2007
  • Identification of ribosomal phosphoprotein P0 of Neospora caninum as a potential common vaccine candidate for the control of both neosporosis and toxoplasmosis, Houshuang Zhang; Eung-goo Lee; Min Liao; Muller K. A. Compaore; Guohong Zhang; Osamu Kawase; Kozo Fujisaki; Chihiro Sugimoto; Yoshifumi Nishikawa; Xuenan Xuan, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 153(2), 141-148, Jun. 2007
  • PKA activation in concert with ARIS and asterosap induces the acrosome reaction in starfish, M. Sadiqul Islam; O. Kawase; S. Hase; M. Hoshi; M. Matsumoto, ZYGOTE, 14(4), 329-340, Nov. 2006
  • Na+/Ca2+ exchanger contributes to asterosap-induced elevation of intracellular Ca2+ concentration in starfish spermatozoa, M. Sadiqul Islam; Osamu Kawase; Sumitaka Hase; Hiroyuki Minakata; Motonori Hoshi; Midori Matsumoto, ZYGOTE, 14(2), 133-141, May 2006
  • Asterosap-induced elevation in intracellular pH is indispensable for ARIS-induced sustained increase in intracellular Ca2+ and following acrosome reaction in starfish spermatozoa, O Kawase; H Minakata; M Hoshi; M Matsumoto, ZYGOTE, 13(1), 63-71, Feb. 2005
  • Guanylyl cyclase and cGMP-specific phosphodiesterase participate in the acrosome reaction of starfish sperm, O Kawase; S Ueno; H Minakata; M Hoshi; M Matsumoto, ZYGOTE, 12(4), 345-355, Nov. 2004
  • A sperm-activating peptide controls a cGMP-signaling pathway in starfish sperm, M Matsumoto; J Solzin; A Helbig; Hagen, V; S Ueno; O Kawase; Y Maruyama; M Ogiso; M Godde; H Minakata; UB Kaupp; M Hoshi; Weyand, I, DEVELOPMENTAL BIOLOGY, 260(2), 314-324, Aug. 2003
  • Biosynthesis of polyoxypeptin A: novel amino acid 3-hydroxy-3-methylproline derived from isoleucine, K Umezawa; Y Ikeda; O Kawase; H Naganawa; S Kondo, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, (13), 1550-1553, 2001
    Review paper
  • Robot-Assisted Emergency Supports in Minamisanriku after the Eastern Japan Earthquake, 川瀬 摂, 日本ロボット学会誌 = Journal of the Robotics Society of Japan, 32(2), 125-128, Mar. 2014
  • Application of Robot Technologies to The Disaster Sites, Acceptance Example in Local Government, Osamu Kawase, Report of the Great East Japan Earthquake Disaster, Mechanical Engineering Volume, 2013
  • Situation of Shizugawa Nature Center after the Northeastern Japan Earthquake, 川瀬 摂, Aquabiology, 33(5), 410-415, Oct. 2011
  • Regulation of the starfish sperm acrosome reaction by cGMP, pH, cAMP and Ca2+, Midori Matsumoto; Osamu Kawase; M. Sadiqul Islam; Masahiro Naruse; Shin-Nosuke Watanabe; Riho Ishikawa; Motonori Hoshi, INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 52(5-6), 523-526, 2008
    Other
  • The concerted regulation of acrosome reaction in starfish by intracellular cGMP, cAMP and Ca2+ level, Matsumoto M; Kawase O; Islam MS; Naruse M; Hoshi M, Proceedings of the 13th International Echinoderm Conference, 263-263, Oct. 2012
  • Asterosap-induced calcium entry mechanism is much more sensitive to cGMP than to cAMP, M Matsumoto; O Kawase; M Hoshi, PROCEEDING OF 9TH INTERNATIONAL SYMPOSIUM ON SPERMATOLOGY, 77-80, 2002

Presentations

  • Detection and Characterization of Antisperm Antibodies in Japanese Sika Deer., Kawase O, 22nd International Congress of Zoology and 87th Meeting of Zoological Society of Japan, 2016, Okinawa, Japan, True
  • Praeaplocoma sp. (Echinodermata, Ophiuroidea) from the lower Triassic of Japan., Ishida Y, Kotake N, Thuy B, Fujita T, Kawase, European Echinoderms Colloquium, 2014, Portsmouth, United Kingdom, True
  • 震災が奪ったもうひとつの機能「南三陸町自然環境活用センター」を語るフォーラム, 2012, Public discourse, Japan, False
  • The concerted regulation of acrosome reaction in starfish by intracellular pH, cAMP and Ca2+ level., Matsumoto M, Kawase O, Islam MS, Naruse M, Hoshi M, 13th International Echinoderm Conference, 2009, Tasmania, Australia, True
  • Characterization of Salmonella isolated from slaughter pigs in Hokkaido, Japan and potential transfer of antimicrobial resistance genes., Thuy NTB, Takeshi K, Minami A, Maklon K, Kawase O, Makino S, Kawamoto K, MSK's 50th Anniversary International Symposium on Microbiology, 2009, Jeju, Korea, Republic of, True
  • Isolation and characterization of Listeria monocytogenes from Asazuke (Japanese light pickles)., Maklon K, Minami A, Thuy NTB, Kagawa M, Kawase O, Takeshi K, Makino S, Kawamoto K, MSK's 50th Anniversary International Symposium on Microbiology, 2009, Jeju, Korea, Republic of, True
  • Proteomic analysis of calcium-dependent secretion in Toxoplasma gondii., Kawase O, Parasite Vector Genomics Mini Symposium II, 2008, Obihiro, Japan, True
  • Analysis of proteins released by calcium-dependent secretion in Toxoplasma gondii., Kawase O, Nishikawa Y, Lee EG, Xuan X, The 15th Japanese-German Symposium on Protozoan Diseases, 2006, Obihiro, Japan, True
  • Inhibition of lipopolysaccharide activity by heptadepsin, a novel cyclic depsipeptide isolated from Paenibacillus sp., Ohno O, Suzuki Y, Kawase O, Matsumoto M, Umezawa K, International Union for Biochemistry and Molecular Biology 8th Conference / American Society for Biochemistry and Molecular Biology Annual Meeting, 2004, Boston, United States, True
  • Asterosap-induced increase of intracellular pH is indispensable for the sustained elevation of intracellular Ca2+ induced by ARIS and following acrosome reaction in starfish spermatozoa., Kawase O, Matsumoto M, Hoshi M, 0th International Congress on Invertebrate Reproduction and Development, 2004, Newcastle upon Tyne, United Kingdom, True
  • Effect of PKA-mediated phosphorylation on acrosome reaction in starfish., Islam MS, Kawase O, Hoshi M, Matsumoto M, The 4th International Symposium on the Molecular and Cell Biology of Egg- and Embryo-Coats, 2004, Shima, Japan, False
  • The acrosome reaction is cooperatively induced by ARIS and asterosap in starfish sperm., Kawase O, Hoshi M, Matsumoto M, The 4th International Symposium on the Molecular and Cell Biology of Egg- and Embryo-Coats, 2004, Shima, Japan, True
  • Asterosap facilitates the acrosome reaction via cGMP in starfish spermatozoa., Kawase O, Matsumoto M, Hoshi M, Gordon Research Conference on Fertilization and Activation of Development, 2003, Plymouth, United States, True
  • A sperm-activating peptide controls a cGMP-signaling pathway in starfish sperm., Helbig A, Solzin J, Hagen V, Ueno S, Kawase O, Maruyama Y, Ogiso M, Godde M, Minakata H, Kaupp UB, Hoshi M, Weyand I, Matsumoto M, Developmental Biology of the Sea Urchin XV, 2003, Woods Hole, United States, True
  • The effect of cGMP on the acrosome reaction of starfish spermatozoa., Kawase O, Matsumoto M, Hoshi M, International symposium of 21st century COE Program, Keio University on Understanding and Control of Life’s Function via System Biology, 2003, Yokohama, Japan, True
  • Asterosap-induced calcium entry mechanism is much more sensitive to cGMP than to cAMP., Matsumoto M, Kawase O, Hoshi M, 9th International Symposium on Spermatology, 2002, Cape Town, South Africa, True

Social contributions

Media Coverage

  • 2014
  • 2012

University administration

学内委員会等活動

  • 2023, 2023
  • 2023, 2023
  • 2021, 2023
  • 2019, 2023
  • 2019, 2023
  • 2015, 2017
  • 2015, 2017
  • 2014, 2016
  • 2014, 2015
  • 2012, 2023


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