Researchers Database
NIHO SEIJI
Affiliation： Department of Pulmonary Medicine and Clinical Immunology Position： Professor | |||
Last Updated :2026/04/21
Research achievements
Published Papers
- A case of spindle cell dominant histiocytic sarcoma showing a complete remission after first-line chemotherapy with doxorubicin and ifosfamide., Nakamura Y, Takemasa A, Kushima Y, Soda S, Ikeda N, Arai R, Chibana K, Nakazato Y, Yokose T, Shimizu Y, Niho S, J Chemother, 20, 1-6, Nov. 2020
- Age and Smoking Predict Antibody Titres at 3 Months after the Second Dose of the BNT162b2 COVID-19 Vaccine., Nomura Yushi;Sawahata Michiru;Nakamura Yosikazu;Kurihara Momoko;Koike Ryousuke;Katsube Otohiro;Hagiwara Koichi;Niho Seiji;Masuda Norihiro;Tanaka Takaaki;Sugiyama Kumiya, Vaccines, 9(9), 18 Sep. 2021
- Attenuation of Antibody Titers from 3 to 6 Months after the Second Dose of the BNT162b2 Vaccine Depends on Sex, with Age and Smoking Risk Factors for Lower Antibody Titers at 6 Months., Nomura Yushi;Sawahata Michiru;Nakamura Yosikazu;Koike Ryousuke;Katsube Otohiro;Hagiwara Koichi;Niho Seiji;Masuda Norihiro;Tanaka Takaaki;Sugiyama Kumiya, Vaccines, 9(12), 18 Dec. 2021
- Carboplatin plus nab-paclitaxel for recurrent small cell lung cancer: A phase II study., Ikeda Naoya;Arai Ryo;Soda Sayo;Inoue Takashi;Uchida Nobuhiko;Nakamura Yusuke;Masawa Meitetsu;Kushima Yoshitomo;Okutomi Hiroaki;Takemasa Akihiro;Shimizu Yasuo;Niho Seiji, Thoracic cancer, 13(9), 1342-1348, 22 Mar. 2022
Original paper
- Next-generation sequencing analyses using biopsy forceps and cytology brush rinse fluids for lung cancer genotyping: Report of five cases., Nakazato Yoshimasa;Machida Hiromi;Horii Yukimi;Onozaki Masato;Ohikata Kensuke;Kaneko Yuko;Arai Ryo;Niho Seiji;Ishida Kazuyuki, Diagnostic cytopathology, 49(10), 1148-1149, Oct. 2021
Case report
- Impact of Adding Vascular Endothelial Growth Factor Inhibitor to Immune Checkpoint Inhibitor Therapy., Niho Seiji, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 17(7), 865-866, Jul. 2022
- REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma., Masawa Meitetsu;Sato-Yazawa Hanako;Kashiwagi Korehito;Ishii Jun;Miyata-Hiramatsu Chie;Iwamoto Masami;Kohno Kakeru;Miyazawa Tadasuke;Onozaki Masato;Noda Shuhei;Shimizu Yasuo;Niho Seiji;Yazawa Takuya, The American journal of pathology, 192(6), 847-861, 30 Mar. 2022
- Creation of an Integrated Clinical Trial Database and Data Sharing for Conducting New Research by the Japan Lung Cancer Society., Ozawa Yuichi;Yamamoto Nobuyuki;Yamamoto Kouji;Ito Kentaro;Kenmotsu Hirotsugu;Hayashi Hidetoshi;Shukuya Takehito;Fujimoto Daichi;Sugawara Shunichi;Niho Seiji;Ohe Yuichiro;Okamoto Hiroaki;Nakagawa Kazuhiko;Kiura Katsuyuki;Yoshino Ichiro;Gemma Akihiko, JTO clinical and research reports, 3(5), 100317, 27 Mar. 2022
- Systemic Adverse Effects Induced by the BNT162b2 Vaccine Are Associated with Higher Antibody Titers from 3 to 6 Months after Vaccination., Koike Ryousuke;Sawahata Michiru;Nakamura Yosikazu;Nomura Yushi;Katsube Otohiro;Hagiwara Koichi;Niho Seiji;Masuda Norihiro;Tanaka Takaaki;Sugiyama Kumiya, Vaccines, 10(3), 15 Mar. 2022
- Concurrent chemoradiotherapy with cisplatin + S-1 versus cisplatin + other third-generation agents for locally advanced non-small-cell lung cancer: a meta-analysis of individual participant data., Taniguchi Yuri;Okamoto Hiroaki;Shimokawa Tsuneo;Sasaki Tomonari;Seto Takashi;Niho Seiji;Ohe Yuichiro;Saigusa Yusuke, BMC pulmonary medicine, 22(1), 31, 09 Jan. 2022
- Metabolic changes induced by TGF-β1 via reduced expression of phosphatidylserine decarboxylase during myofibroblast transition., Uchida Nobuhiko;Shimizu Yasuo;Fujimaki Mio;Horibata Yasuhiro;Nakamura Yusuke;Horigane Yukiko;Chibana Kazuyuki;Takemasa Akihiro;Sugimoto Hiroyuki;Niho Seiji, Journal of clinical biochemistry and nutrition, 70(2), 108-116, 03 Dec. 2021
- Changes in Peripheral Blood Eosinophil Counts and Risk of Eosinophilic Granulomatosis with Polyangiitis Onset after Initiation of Dupilumab Administration in Adult Patients with Asthma., Kushima Yoshitomo;Shimizu Yasuo;Hoshi Hiromi;Arai Ryo;Ikeda Naoya;Nakamura Yusuke;Masawa Meitetsu;Okutomi Hiroaki;Yazawa Nana;Chibana Kazuyuki;Takemasa Akihiro;Niho Seiji, Journal of clinical medicine, 12(17), 01 Sep. 2023
- A Protective Effect of Pirfenidone in Lung Fibroblast-Endothelial Cell Network via Inhibition of Rho-Kinase Activity., Nakamura Yusuke;Shimizu Yasuo;Fujimaki-Shiraishi Mio;Uchida Nobuhiko;Takemasa Akihiro;Niho Seiji, Biomedicines, 11(8), 12 Aug. 2023
- Pulmonary granulomas confirmed in Blau syndrome using TBLC specimens: Case report., Shimizu Yasuo;Kushima Yoshitomo;Tanaka Ayae;Takemasa Akihiro;Ishida Kazuyuki;Niho Seiji, Frontiers in medicine, 11, 1380236, 12 Jun. 2024
- Tezepelumab improved chronic eosinophilic pneumonia in severe asthma patients with liver cirrhosis., Inaba Mizuki;Shimizu Yasuo;Nakamura Yusuke;Okutomi Hiroaki;Takemasa Akihiro;Niho Seiji, Frontiers in medicine, 11, 1381261, 11 Jun. 2024
- Cell-Based Therapy for Fibrosing Interstitial Lung Diseases, Current Status, and Potential Applications of iPSC-Derived Cells., Nakamura Yusuke;Niho Seiji;Shimizu Yasuo, Cells, 13(11), 22 May 2024
- Clinical outcomes in patients with non-small cell lung cancer harboring EGFR Exon20 in-frame insertions in the near-loop and far-loop: Results from LC-SCRUM-Asia., Okahisa Masanobu;Udagawa Hibiki;Matsumoto Shingo;Kato Terufumi;Yokouchi Hiroshi;Furuya Naoki;Kanemaru Ryota;Toyozawa Ryo;Nishiyama Akihiro;Ohashi Kadoaki;Miyamoto Shingo;Nishino Kazumi;Nakamura Atsushi;Iwama Eiji;Niho Seiji;Oi Hajime;Sakai Tetsuya;Shibata Yuji;Izumi Hiroki;Sugiyama Eri;Nosaki Kaname;Umemura Shigeki;Zenke Yoshitaka;Yoh Kiyotaka;Kah Mun Low Grace;Zhuo Jianmin;Goto Koichi, Lung cancer (Amsterdam, Netherlands), 191, 107798, 23 Apr. 2024
- Long-term follow-up and exploratory analysis of lenvatinib in patients with metastatic or recurrent thymic carcinoma: Results from the multicenter, phase 2 REMORA trial., Niho Seiji;Sato Jun;Satouchi Miyako;Itoh Shoichi;Okuma Yusuke;Mizugaki Hidenori;Murakami Haruyasu;Fujisaka Yasuhito;Kozuki Toshiyuki;Nakamura Kenichi;Machida Ryunosuke;Ohe Yuichiro;Tamai Toshiyuki;Ikezawa Hiroki;Yamamoto Noboru, Lung cancer (Amsterdam, Netherlands), 191, 107557, 30 Mar. 2024
- Association between skin toxicity and efficacy of necitumumab in squamous non-small-cell lung cancer: a pooled analysis of two randomized clinical trials-SQUIRE and JFCM., Watanabe S;Yoshioka H;Sakai H;Hotta K;Takenoyama M;Yamada K;Sugawara S;Takiguchi Y;Hosomi Y;Tomii K;Niho S;Nishio M;Kato T;Takahashi T;Ebi H;Aono M;Yamamoto N;Ohe Y;Nakagawa K, ESMO open, 9(4), 102975, 22 Mar. 2024
- Corrigendum to "Transcutaneous gas monitoring is a useful tool to detect respiratory depression during bronchoscopy performed under propofol sedation" [Resp. Invest. 61 (2023) 793-799]., Yazawa Nana;Nakamura Yusuke;Takemasa Akihiro;Uchida Nobuhiko;Kushima Yoshitomo;Masawa Meitetsu;Okutomi Hiroaki;Soda Sayo;Ikeda Naoya;Arai Ryo;Chibana Kazuyuki;Niho Seiji;Shimizu Yasuo, Respiratory investigation, 62(2), 295, 30 Jan. 2024
- Transcutaneous gas monitoring is a useful tool to detect respiratory depression during bronchoscopy performed under propofol sedation., Yazawa Nana;Nakamura Yusuke;Takemasa Akihiro;Uchida Nobuhiko;Kushima Yoshitomo;Masawa Meitetsu;Okutomi Hiroaki;Soda Sayo;Ikeda Naoya;Arai Ryo;Chibana Kazuyuki;Niho Seiji;Shimizu Yasuo, Respiratory investigation, 61(6), 793-799, 27 Sep. 2023
- Phase III study of ramucirumab plus docetaxel versus atezolizumab for previously treated PD-L1 low or negative advanced non-small-cell lung cancer: WJOG10317L study., Zenke Yoshitaka;Niho Seiji;Toi Yukihiro;Yamaguchi Masafumi;Hara Satoshi;Akazawa Yuki;Hosomi Yukio;Yonesaka Kimio;Akamatsu Hiroaki;Yokoyama Toshihide;Tanizaki Junko;Ueno Kiyonobu;Gyotoku Hiroshi;Misumi Toshihiro;Nakagawa Kazuhiko;Yamamoto Nobuyuki;Tsuboi Masahiro, Lung cancer (Amsterdam, Netherlands), 206, 108633, 23 Jun. 2025
- Randomized Phase III Study of EGFR Tyrosine Kinase Inhibitor and Intercalated Platinum-Doublet Chemotherapy for Non-Small Cell Lung Cancer Harboring EGFR Mutation., Kanda Shintaro;Niho Seiji;Kurata Takayasu;Nomura Shogo;Kawashima Yosuke;Iwama Eiji;Yokoyama Toshihide;Watanabe Yasutaka;Tanaka Hiroshi;Fujiwara Yutaka;Zenke Yoshitaka;Azuma Koichi;Taniguchi Hirokazu;Toyozawa Ryo;Hosomi Yukio;Murakami Haruyasu;Hara Satoshi;Bessho Akihiro;Yamamoto Nobuyuki;Ohe Yuichiro, Clinical cancer research : an official journal of the American Association for Cancer Research, 31(12), 2317-2326, 13 Jun. 2025
- A Case of Cryobiopsy of a Large Allergic Bronchopulmonary Aspergillosis-Associated Mucus Plug., Nakamura Yusuke;Goto Yuto;Tsukada Nobuhiko;Tsukada Azusa;Uchida Nobuhiko;Yazawa Nana;Shimizu Yasuo;Niho Seiji, Respirology case reports, 13(6), e70221, 03 Jun. 2025
- Treatment of small cell lung cancer; advances and future prospects., Niho Seiji, Respiratory investigation, 63(4), 680-685, 29 May 2025
- A treatment-related death predictive score for treatment-naïve advanced non-small cell lung cancer., Nomura Shogo;Sekino Yuta;Shiraishi Yoshimasa;Toi Yukihiro;Yoshida Tatsuya;Tanaka Kentaro;Suzuki Shinichiro;Azuma Koichi;Hara Satoshi;Morita Ryo;Niho Seiji;Koda Takuyuki;Toyozawa Ryo;Yoh Kiyotaka;Kurata Takayasu;Fukuda Haruhiko;Ohe Yuichiro;Okamoto Isamu, Lung cancer (Amsterdam, Netherlands), 204, 108584, 16 May 2025
- Dysregulated metabolic pathways of pulmonary fibrosis and the lipids associated with the effects of nintedanib therapy., Shimizu Yasuo;Horibata Yasuhiro;Domae Mariko;Nakamura Yusuke;Yokoyama Tatsuya;Arai Ryo;Shiobara Taichi;Takemasa Akihiro;Koike Ryosuke;Uchida Nobuhiko;Masawa Meitetsu;Tei Rinna;Watanabe Taiji;Morita Hiroko;Miyoshi Masaaki;Soda Sayo;Niho Seiji;Igami Ko;Sugimoto Hiroyuki, Respiratory research, 26(1), 166, 28 Apr. 2025
- Real-life effectiveness of once-daily single-inhaler triple therapy (FF-UMEC-VI) after switching from dual therapy (ICS-LABA) in patients with symptomatic asthma: trelegy ellipta for real asthma control study., Kushima Yoshitomo;Shimizu Yasuo;Arai Ryo;Chibana Kazuyuki;Shimizu Yuka;Amagai Masahiro;Takemasa Akihiro;Ikeda Naoya;Masawa Meitetsu;Kushima Atsushi;Okutomi Hiroaki;Nakamura Yusuke;Tei Rinna;Ando Yuki;Yazawa Nana;Goto Yuto;Haruyama Yasuo;Yukawa Tatsuo;Niho Seiji, Frontiers in allergy, 6, 1537501, 17 Mar. 2025
- Gut Microbiota in Advanced NSCLC Receiving Chemoimmunotherapy: An Ancillary Biomarker Study From the Phase III Trial JCOG2007 (NIPPON)., Hakozaki Taiki;Tanaka Kentaro;Shiraishi Yoshimasa;Sekino Yuta;Mitome Noriko;Okuma Yusuke;Aiba Tomoiki;Utsumi Takahiro;Tanizaki Junko;Azuma Koichi;Hara Satoshi;Morita Ryo;Niho Seiji;Yokoyama Toshihide;Toyozawa Ryo;Horinouchi Hidehito;Okamoto Isamu;Hosomi Yukio;Ohe Yuichiro, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 20(7), 912-927, 07 Mar. 2025
- Acute Liver Failure Caused by Isoniazid during Preventive Treatment for Latent Tuberculosis: A Rare Autopsy Case Report., Yamazaki Yuka;Tominaga Keiichi;Arisaka Takahiro;Tagaya Mayuko;Kojimahara Shunsuke;Ohnishi Toshihiko;Majima Yuichi;Yamamiya Akira;Iijima Makoto;Ikeda Naoya;Niho Seiji;Noda Shuhei;Ishida Kazuyuki;Irisawa Atsushi, Internal medicine (Tokyo, Japan), 64(14), 2160-2164, 19 Dec. 2024
- A case of acute eosinophilic pneumonia induced by the inhalation of acetylene., Tsukada Nobuhiko;Nakamura Yusuke;Hara Shohei;Honda Arata;Tsukada Azusa;Takaaki Majima;Tsuchiya Midori;Wake Koji;Shimizu Yasuo;Niho Seiji, Respiratory medicine case reports, 52, 102135, 23 Oct. 2024
- A case of pulmonary mucosa-associated lymphoid tissue lymphoma diagnosed by detecting t(11;18)(q21;q21) in bronchial lavage fluid., Nakamura Yusuke;Takemasa Akihiro;Ohoka Yuki;Tsukada Nobuhiko;Tsukada Azusa;Nakazato Yoshimasa;Mitani Kinuko;Toyoda Akihiko;Shimizu Yasuo;Niho Seiji, Respiratory medicine case reports, 52, 102133, 17 Oct. 2024
- Effectiveness of trastuzumab deruxtecan rechallenge in a patient with HER2-positive metastatic breast cancer: a case report., Tanaka Yuko;Ikeda Naoya;Niho Seiji;Ishida Kazuyuki, International cancer conference journal, 13(4), 353-359, 10 Sep. 2024
- Comparison of platinum combination chemotherapy plus pembrolizumab versus platinum combination chemotherapy plus nivolumab-ipilimumab for treatment-naive advanced non-small-cell lung cancer in Japan (JCOG2007): an open-label, multicentre, randomised, phase 3 trial., Shiraishi Yoshimasa;Nomura Shogo;Sugawara Shunichi;Horinouchi Hidehito;Yoneshima Yasuto;Hayashi Hidetoshi;Azuma Koichi;Hara Satoshi;Niho Seiji;Morita Ryo;Yamaguchi Masafumi;Yokoyama Toshihide;Yoh Kiyotaka;Kurata Takayasu;Okamoto Hiroaki;Okamoto Masaki;Kijima Takashi;Kasahara Kazuo;Fujiwara Yutaka;Murakami Shuji;Kanda Shintaro;Akamatsu Hiroaki;Takemoto Shinnosuke;Kaneda Hiroyasu;Kozuki Toshiyuki;Ando Masahiko;Sekino Yuta;Fukuda Haruhiko;Ohe Yuichiro;Okamoto Isamu, The Lancet. Respiratory medicine, 12(11), 877-887, 16 Aug. 2024
- Phase II study of brigatinib in patients with ROS1 fusion-positive non-small-cell lung cancer: the Barossa study., Niho S;Goto Y;Toyozawa R;Daga H;Ohashi K;Takahashi T;Tanaka H;Sakakibara-Konishi J;Hattori Y;Morise M;Kodani M;Ikeda T;Izumi H;Matsumoto S;Yoh K;Nomura S;Goto K, ESMO open, 9(8), 103642, 16 Jul. 2024
- A Case of Bronchoscopic Removal of Aspergilloma in Patients With Non-Surgical Indications., Tetsuka Takatoshi;Nakamura Yusuke;Goto Yuto;Mikura Sunao;Yazawa Nana;Suzuki Hiromichi;Shimizu Yasuo;Niho Seiji, Respirology case reports, 13(8), e70310, 04 Aug. 2025
- [Bronchoscopic Lung Volume Reduction for Severe Chronic Obstructive Lung Disease]., Nakajima Takahiro;Inoue Takashi;Okutomi Hiroaki;Takemasa Akihiro;Shimizu Yasuo;Maeda Sumiko;Niho Seiji;Chida Masayuki, Kyobu geka. The Japanese journal of thoracic surgery, 78(7), 497-502, Jul. 2025
- [A CASE OF FIBROTIC HYPERSENSITIVITY PNEUMONITIS IN WHICH A DRUG-INDUCED LYMPHOCYTE STIMULATION TEST FOR ISOCYANATE (HEXAMETHYLENE DIISOCYANATE) REAGENT WAS CONTRIBUTED TO DIAGNOSIS]., Nakamura Yusuke;Inaba Mizuki;Goto Yuto;Yazawa Nana;Tsukada Nobuhiko;Tsukada Azusa;Ooka Yuki;Matsuda Hadzki;Ishida Kazuyuki;Arakawa Hiroaki;Niho Seiji;Shimizu Yasuo, Arerugi = [Allergy], 74(5), 271-276, 2025
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