Researchers Database
HASHIMOTO KOSHI
Affiliation： Department of Diabetes, Endocrinology and Hematology Position： Professor | |||
Last Updated :2025/04/28
Research achievements
Published Papers
- Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing., Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y., Sci Rep, 10(1), 5181, Mar. 2020
- Clinical outcomes of 20 Japanese patients with insulinoma treated with diazoxide., Niitsu Y, Minami I, Izumiyama H, Hashimoto K, Yoshimoto T, Sato F, Tsujino M, Ota K, Kudo A, Tanabe M, Yamada T, Ogawa Y, Endocr J, 66(2), 149-155, 01 Feb. 2019
- Analysis of time-dependent changes in the FIB4 index in patients with obesity receiving weight reduction therapy．, Kawai S，Yamakage H，Kotani K，Noda M，Satoh-Asahara N，Hashimoto K, Sci Rep., 12(1), Sep. 2022
- Seasonal variations and the influence of COVID-19 pandemic on hemoglobin A1c，glycoalbumin，and low-density lipoprotein cholesterol．, Takebayashi K，Yamauchi M，Hara K，Tsuchiya T，Hashimoto K, Diabetol Int., 13(4), 599-605, Oct. 2022
- Association of skin autofluorescence with serum lipids, insulin secretion ability and diabetic complications in patients with poorly controlled type 2 diabetes., Takebayashi K, Tsuchiya T, Shinozaki H, Yamauchi M, Suzuki T, Hara K, Inukai T, Hashimoto K, Dokkyo Med J., 2022
- Switching from a dipeptidyl peptidase (DPP)-4 inhibitor to oral semaglutide in patients with poorly controlled type 2 diabetes: an observational study., Takebayashi K, Yamauchi M, Hara K, Tsuchiya T, Hashimoto K., Dokkyo Med J., 2022
- In Vivo Tissue-Specific DNA Demethylation in Mouse Liver Through a Hydrodynamic Tail Vein Injection, Hashimoto K，Hanzawa N, Methods Mol Biol, 2577, 269-277, 2023
- Differences in metabolic characteristics between Metabolically Healthy Obesity (MHO) and Metabolically Unhealthy Obesity (MUO) in weight reduction therapy., Kawai S, Yamakage H, Kotani K, Noda M, Satoh-Asahara N, Hashimoto K(corresponding), Endocr J, 70, 1175-1186, 2023
- In Vivo Tissue-Specific DNA Demethylation in Mouse Liver Through a Hydrodynamic Tail Vein Injection., Hashimoto K, Hanzawa N, Methods Mol Biol., 2577, 269-277, 2023
- Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity., Hara K, Ujiie A, Suzuki S, Okumura T, Kubo M, Shinozaki H, Yamauchi M, Tsuchiya T, Takebayashi K, Shimozawa N, Koga M, Hashimoto K, Endocr J, 2023
- Effects of telemedicine on the management of diabetes mellitus in the COVID-19 pandemic- A single center study-., Furukawa S, Kawai S, Yamauchi M, Shinozaki H, Ujiie A, Okumura T, Kubo M, Suzuki S, Asai K, Takii H, Hara K, Miyakawa K, Hara K, Tsuchiya T, Takebayashi K, Hashimoto K, Dokkyo Med J., 2023
- Differences in metabolic characteristics between Metabolically Healthy Obesity (MHO) and Metabolically Unhealthy Obesity (MUO) in weight reduction therapy., Kawai S, Yamakage H, Kotani K, Noda M, Satoh-Asahara N, Hashimoto K, Endocr J., 70, 1175-1186, Dec. 2023
- In Vivo Tissue-Specific DNA Demethylation in Mouse Liver Through a Hydrodynamic Tail Vein Injection., Hashimoto K, Hanzawa N, Methods Mol Biol., 2577, 269-277, 2023
- Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity., Hara K, Ujiie A, Suzuki S, Okumura T, Kubo M, Shinozaki H, Yamauchi M, Tsuchiya T, Takebayashi K, Shimozawa N, Koga M, Hashimoto K, Endocr J., 71, 39-44, 2024
- Changing from a Dipeptidyl Peptidase (DPP)-4 Inhibitor to Oral Semaglutide in Patients with Poorly Controlled Type 2 Diabetes Mellitus: An Observational Study., Takebayashi K, Yamauchi M, Hara K, Tsuchiya T, Hashimoto K., Dokkyo Medical J., 2(Jun), 123-129, 2023
Original paper
- Update on subclinical thyroid dysfunction, Hashimoto K．, Endocr J., 69(7), 725-738, 28 Jul. 2022
- 24(2), 6-6, Oct. 2022
- 111(5), 583-588, 01 May 2023
- 53(2), 37-42, 2023
- Preemptive medicine for Diabetes from the viewpoint of the DOHaD theory., Hashimoto K., Dokkyo Medical J., 2023
- 113(3), 516-521, 2023
- 45(4), 194-205, 2023
- 57(3), 284-291, 2023
- 132(2), 204-207, 2023
- 53(2), 37-42, 2023
- 286(10), 850-854, 2023
- 111(5), 583-588, 2023
- 56(3), 334-339, 2023
Review paper
- A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles., Fukaishi T, Minami I, Masuda S, Miyachi Y, Tsujimoto K, Izumiyama H, Hashimoto K, Yoshida M, Takahashi S, Kashimada K, Morio T, Kosaki K, Maezawa Y, Yokote K, Yoshimoto T, Yamada T., Endocr J, 67(2), 211-218, 01 Feb. 2020
- A case of refractory hypothyroidism due to poor compliance treated with the weekly intravenous and oral levothyroxine administration., Nakano Y, Hashimoto K, Ohkiba N, Okuma H, Minami I, Takahashi H, Tanaka Y, Yoshimoto T, Yamada T, Case Rep Endocrinol, 2019(5), 5986014-5986014, 01 Feb. 2019
- Severe Non-Islet Cell Hypoglycemia From Ileum-Origin Gastrointestinal Stromal Tumor Producing Insulin-Like Growth Factor-2 in a Patient With Liver Cirrhosis Due to Chronic Hepatitis B, Takebayashi K, Furukawa S, Okumura T, Kubo M, Ujiie A, Yamauchi M, Shinozaki H, Hara K, Tsuchiya T, Ono Y, Inukai T, Hashimoto K, J Clin Med Res., 12, 824-830, 18 Dec. 2020
- A case of persistent SARS-CoV-2 PCR positive after chemotherapy for B-cell lymphoma．, Hirokawa H，Hirata H，Kitajima R，Irokawa M，Ishiguro T，Hasegawa T，Sato J， Ozaki A，Arima M，Teramoto S，Haruki K，Okamura T，Tamura H，Hashimoto K， Fukushima Y., Dokkyo Med J., 1(2), 141-146, Jun. 2022
- Furukawa S, Kawai S, Yamauchi M, Shinozaki H, Ujiie A, Okumura T, Kubo M, Suzuki S, Asai K, Takii H, Hara K, Miyakawa K, Hara K, Tsuchiya T, Takebayashi K, Hashimoto K, 2(Jun), 64-66, 2023
Case report