Researchers Database
SAWANOBORI YASUSHI
Position： Assistant Professor | |||
Last Updated :2025/04/28
Research achievements
Published Papers
- 43(1), 91-103, Mar. 2016
- 44(3), 227-234, Oct. 2017
- Direct evidence for activated CD8+ T cell transmigration across portal vein endothelial cells in liver graft rejection., Kariya Taro;Ueta Hisashi;Xu Xue-Dong;Koga Daisuke;Ezaki Taichi;Yu Enqiao;Kusumi Satoshi;Kitazawa Yusuke;Sawanobori Yasushi;Ushiki Tatsuo;Issekutz Thomas;Matsuno Kenjiro, Journal of gastroenterology, 51(10), 985-998, Oct. 2016
- Anatomical basis for simultaneous block of greater and third occipital nerves, with an ultrasound-guided technique., Kariya Ken;Usui Yosuke;Higashi Naoko;Nakamoto Tatsuo;Shimbori Hironobu;Terada Satoshi;Takahashi Hideo;Ueta Hisashi;Kitazawa Yusuke;Sawanobori Yasushi;Okuda Yasuhisa;Matsuno Kenjiro, Journal of anesthesia, 32(4), 483-492, 2018
- Rapid immunosurveillance by recirculating lymphocytes in the rat intestine: critical role of unsulfated sialyl-Lewis X on high endothelial venules of the Peyer's patches., Uchida Tomomi;Ueta Hisashi;Xu Xue-Dong;Hirakawa Jotaro;Tahara Kazunori;Zhou Shu;Sawanobori Yasushi;Simmons Szandor;Kitazawa Yusuke;Kawashima Hiroto;Matsuno Kenjiro, International immunology, 30(1), 23-33, 2018
- Novel Targeting to XCR1+ Dendritic Cells Using Allogeneic T Cells for Polytopical Antibody Responses in the Lymph Nodes., Kitazawa Yusuke;Ueta Hisashi;Sawanobori Yasushi;Katakai Tomoya;Yoneyama Hiroyuki;Ueha Satoshi;Matsushima Kouji;Tokuda Nobuko;Matsuno Kenjiro, Frontiers in immunology, 10, 1195, 2019
- Suppression of liver transplant rejection by anti-donor MHC antibodies via depletion of donor immunogenic dendritic cells., Ueta Hisashi;Xu Xue-Dong;Yu Bin;Kitazawa Yusuke;Yu Enqiao;Hara Yoshiaki;Morita-Nakagawa Miwa;Zhou Shu;Sawanobori Yasushi;Ueha Satoshi;Rokutan Kazuhito;Tanaka Toshiya;Tokuda Nobuko;Matsushima Kouji;Matsuno Kenjiro, International immunology, 33(5), 261-272, 22 Apr. 2021
- 47(2), 88, Jul. 2020
- Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice., Sawanobori Yasushi;Ueha Satoshi;Kurachi Makoto;Shimaoka Takeshi;Talmadge James E;Abe Jun;Shono Yusuke;Kitabatake Masahiro;Kakimi Kazuhiro;Mukaida Naofumi;Matsushima Kouji, Blood, 111(12), 5457-5466, 28 Mar. 2008
- Anti-interleukin-31-antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis., Grimstad Oystein;Sawanobori Yasushi;Vestergaard Christian;Bilsborough Janine;Olsen Uffe Bang;Grønhøj-Larsen Christian;Matsushima Kouji, Experimental dermatology, 18(1), 35-43, 24 Oct. 2008
- Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities., Yu Bin;Ueta Hisashi;Kitazawa Yusuke;Tanaka Toshiya;Adachi Kensuke;Kimura Hiromitsu;Morita Miwa;Sawanobori Yasushi;Qian Hai Xin;Kodama Tatsuhiko;Matsuno Kenjiro, Hepatology (Baltimore, Md.), 56(4), 1532-1545, Oct. 2012
- Three distinct subsets of thymic epithelial cells in rats and mice defined by novel antibodies., Sawanobori Yasushi;Ueta Hiashi;Dijkstra Christine D;Park Chae Gyu;Satou Motoyasu;Kitazawa Yusuke;Matsuno Kenjiro, PloS one, 9(10), e109995, 21 Oct. 2014
- A novel multicolor immunostaining method using ethynyl deoxyuridine for analysis of in situ immunoproliferative response., Kitazawa Yusuke;Ueta Hisashi;Hünig Thomas;Sawanobori Yasushi;Matsuno Kenjiro, Histochemistry and cell biology, 144(3), 195-208, 15 May 2015
- Selective involution of thymic medulla by cyclosporine A with a decrease of mature thymic epithelia, XCR1+ dendritic cells, and epithelium-free areas containing Foxp3+ thymic regulatory T cells., Sawanobori Yasushi;Kitazawa Yusuke;Ueta Hisashi;Matsuno Kenjiro;Tokuda Nobuko, Histochemistry and cell biology, 156(2), 133-146, 16 May 2021
Original paper
- The microstructure of secondary lymphoid organs that support immune cell trafficking., Matsuno Kenjiro;Ueta Hisashi;Shu Zhou;Xue-Dong Xu;Sawanobori Yasushi;Kitazawa Yusuke;Bin Yu;Yamashita Masaki;Shi Changde, Archives of histology and cytology, 73(1), 1-21, 2010
Unclear
Presentations
- Analysis of transcriptomes of rat dendritic cell subsets and newly discovered CD103- DC-like cells., Yasushi Sawanobori, Hisashi Ueta, Yusuke Kitazawa, and Nobuko Tokuda., 18 Jan. 2024, 17 Jan. 2024, 19 Jan. 2024, Oral presentation, Japan, Unlike mouse dendritic cells (DCs), rat DCs have been canonically identified with CD103 molecules. However, in an effort to classify MHCII+ cell subsets in rat thymus, we found CD103-CD172a+CD45R- cells. This subset was morphologically similar to conventional DC subsets and commonly existed in peripheral lymphoid tissues, so we named this CD103- DC-like cells provisionally. To characterize CD103- DC-like cells, we performed microarray analyses on conventional DC1s (cDC1s), conventional DC2s (cDC2s), and CD103- DC-like cells isolated from spleens and thymi. Although principal component analysis of the data revealed that CD103- DC-like cells are similar to cDC2s rather than cDC1, CD103- DC-like cells uniquely expressed Fcnb, Cd14, Il1a, Fn1, etc. Regarding differences between organs, thymic CD103- DC-like cells expressed uniquely Mmp14, C3, Apoc1, etc, while splenic CD103- DC-like cells expressed Nos2, Slc11a1, Gda, etc. As CD103- DC-like cells expressed some macrophage/monocyte signature molecules, including Fn1, Ly6c, Cd14, and Mafb, we also compared CD103- DC-like cells with CD163+ macrophages. CD163+ macrophages expressed a broader spectrum of macrophage signature genes than CD103- DC-like cells, including Adgre1, Fcgr3a, and Msr1. Moreover, on a chart of principal component analysis, CD103- DC-like cells and cDCs made a cluster apart from a cluster of the macrophages, suggesting that CD103- DC-like cells are similar to cDCs rather than macrophages., False, Domestic journal
- Identification of rat thymic fibroblasts and their expression of tissue-restricted antigens, Yasushi Sawanobori, Hisashi Ueta, Yusuke Kitazawa, and Nobuko Tokuda, 22 Mar. 2024, 21 Mar. 2024, 23 Mar. 2024, Oral presentation, Japan, It is well known that medullary thymic epithelial cells (mTECs) present tissue-restricted antigens (TRAs) to conduct the selection process of T cells, eventually to prevent autoimmunity. However, several reports indicate that mouse thymic medullary fibroblasts (mFbs) also express TRAs (Nitta 2020, Nitta 2021). Nevertheless, fibroblast distribution and TRA expression are not elucidated in rat thymus. We performed single-cell PCR on rat thymic stromal cells to investigate them. After identifying the mFbs and the mTECs based on Pdgfrb and Aire on in silico analysis and immunohistochemistry, we screened two groups of candidates; the top 50 genes expressed stronger in the rat mFbs than in other thymic fibroblasts (a) and 52 genes indicated in said reports (b). The Human Protein Atlas was referred to to exclude constitutively expressed genes. Within the candidates, 22% and 17% of genes from groups a and b were identified as mFb-associated TRAs, respectively. And 6% and 12% were identified as mFb-mTEC-associated TRAs. These results suggest significant differences in TRA expression between rats and mice and that in vivo experiments are required to overview the TRA expression in rats., False, Domestic journal